Public registry
Nodes
Browse canonical concepts by label, domain, node type, prefix and encoded class.
Current membership scope: Base domain only
| Concept | Node type | Base domain | Matched membership | Identifier |
|---|---|---|---|---|
| Acyl-Butyrolactones Cyclic esters of acylated BUTYRIC ACID containing four carbons in the ring. | Organic Chemical | Biochemistry | Base domain | AMW:CHEM:021736 |
| Acyl-Carrier Protein S-Acetyltransferase A enzyme that catalyzes the transfer of acetyl groups from ACETYL CoA to acyl-carrier protein to form COENZYME A and acetyl-acyl-carrier protein. | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:081275 |
| Acyl-Carrier Protein S-Malonyltransferase This enzyme catalyzes the transacylation of malonate from MALONYL CoA to activated holo-ACP, to generate malonyl-(acyl-carrier protein), which is an … | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:081304 |
| Acyl-CoA Dehydrogenase A flavoprotein oxidoreductase that has specificity for medium-chain fatty acids. It forms a complex with ELECTRON TRANSFERRING FLAVOPROTEINS and conv… | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:081108 |
| Acyl-CoA Dehydrogenase, Long-Chain A flavoprotein oxidoreductase that has specificity for long-chain fatty acids. It forms a complex with ELECTRON-TRANSFERRING FLAVOPROTEINS and convey… | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:081109 |
| Acyl-CoA Dehydrogenases Enzymes that catalyze the first step in the beta-oxidation of FATTY ACIDS. | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:081107 |
| Acyl-CoA Oxidase An enzyme that catalyzes the first and rate-determining steps of peroxisomal beta-oxidation of fatty acids. It acts on COENZYME A derivatives of fatt… | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:081110 |
| Acylphosphatase An enzyme that catalyzes the conversion of an acylphosphate and water to a carboxylate and phosphate. | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:080155 |
| Acyltransferases Enzymes from the transferase class that catalyze the transfer of acyl groups from donor to acceptor, forming either esters or amides. (From Enzyme No… | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:081271 |
| Ad26COVS1 A viral vector vaccine designed against SARS-CoV-2 developed by Johnson & Johnson. Its vector encodes the SARS-CoV-2 Spike protein. | Complex Mixture | Biochemistry | Base domain | AMW:CHEM:200092 |
| Adalimumab A humanized monoclonal antibody that binds specifically to TNF-ALPHA and blocks its interaction with endogenous TNF RECEPTORS to modulate INFLAMMATIO… | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:120816 |
| ADAM Proteins A family of membrane-anchored glycoproteins that contain a disintegrin and metalloprotease domain. They are responsible for the proteolytic cleavage … | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:080716 |
| ADAM10 Protein A disintegrin and metalloproteinase domain-containing protein. It cleaves the membrane-bound precursor of TUMOR NECROSIS FACTOR-ALPHA between ALANINE… | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:080718 |
| ADAM12 Protein A disintegrin and metalloproteinase domain-containing protein that is expressed as two alternatively-spliced forms: a long transmembrane form (ADAM12… | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:080717 |
| ADAM17 Protein A disintegrin and metalloproteinase domain-containing protein that cleaves the membrane-bound precursor of TUMOR NECROSIS FACTOR-ALPHA to its mature … | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:080719 |
| Adamantane A tricyclo bridged hydrocarbon. | Organic Chemical | Biochemistry | Base domain | AMW:CHEM:021244 |
| ADAMTS Proteins A subfamily of ADAM proteases that are distinguished by the presence of one or more THROMBOSPONDIN type-1 repeats (TSRs). These are three-strand moti… | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:080720 |
| ADAMTS1 Protein An ADAMTS protease that contains two disintegrin loops and three C-terminal thrombospondin (TS) motifs. It functions as an ANGIOGENESIS INHIBITOR as … | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:080721 |
| ADAMTS13 Protein An ADAMTS protease that contains eight thrombospondin (TS) motifs. It cleaves VON WILLEBRAND FACTOR to control vWF-mediated THROMBOSIS. Mutations in … | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:080722 |
| ADAMTS4 Protein An ADAMTS protease similar to ADAMTS5 PROTEIN. It contains a single C-terminal thrombospondin (TS) motif and cleaves AGGRECAN in CARTILAGE. It may al… | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:080723 |
| ADAMTS5 Protein An ADAMTS protease that contains two C-terminal thrombospondin (TS) motifs. It functions primarily as an aggrecanase, cleaving AGGRECAN in CARTILAGE,… | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:080724 |
| ADAMTS7 Protein An ADAMTS protease that contains four central and four C-terminal thrombospondin (TS) motifs. It binds to and degrades CARTILAGE OLIGOMERIC MATRIX PR… | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:080725 |
| ADAMTS9 Protein An ADAMTS protease that contains 15 THROMBOSPONDIN (TS) motifs. It cleaves the PROTEOGLYCANS AGGRECAN and VERSICAN and also functions in protein tran… | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:080726 |
| Adapalene A naphthalene derivative that has specificity for RETINOIC ACID RECEPTORS. It is used as a DERMATOLOGIC AGENT for the treatment of ACNE. | Organic Chemical | Biochemistry | Base domain | AMW:CHEM:021206 |
| Adapalene, Benzoyl Peroxide Drug Combination A pharmaceutical preparation of adapalene and benzoyl peroxide that is used as a DERMATOLOGIC AGENT for the topical treatment of ACNE. | Organic Chemical | Biochemistry | Base domain | AMW:CHEM:020975 |
| Adaptor Protein Complex 1 A clathrin adaptor protein complex primarily involved in clathrin-related transport at the TRANS-GOLGI NETWORK. | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:122295 |
| Adaptor Protein Complex 2 An adaptor protein complex primarily involved in the formation of clathrin-related endocytotic vesicles (ENDOSOMES) at the CELL MEMBRANE. | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:122296 |
| Adaptor Protein Complex 3 An adaptor protein complex found primarily on perinuclear compartments. | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:122297 |
| Adaptor Protein Complex 4 An adaptor protein complex involved in transport of molecules between the TRANS-GOLGI NETWORK and the endosomal-lysosomal system. | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:122298 |
| Adaptor Protein Complex alpha Subunits A family of large adaptin protein subunits of approximately 100 kDa in size. They have been primarily found as components of ADAPTOR PROTEIN COMPLEX … | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:122300 |