Public registry
Nodes
Browse canonical concepts by label, domain, node type, prefix and encoded class.
Current membership scope: Base domain only
| Concept | Node type | Base domain | Matched membership | Identifier |
|---|---|---|---|---|
| Basic Helix-Loop-Helix Leucine Zipper Transcription Factors A family of transcription factors that contain regions rich in basic residues, LEUCINE ZIPPER domains, and HELIX-LOOP-HELIX MOTIFS. | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:121433 |
| Basic Helix-Loop-Helix Proteins A class of proteins that include basic HELIX-LOOP-HELIX MOTIFS that generally allow them to bind DNA and act as TRANSCRIPTION FACTORS. | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:121432 |
| Basic-Leucine Zipper Transcription Factors A large superfamily of transcription factors that contain a region rich in BASIC AMINO ACID residues followed by a LEUCINE ZIPPER domain. | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:121451 |
| Basigin A widely distributed cell surface transmembrane glycoprotein characterized by extracellular IMMUNOGLOBULIN DOMAINS. It stimulates the synthesis of MA… | Carbohydrate | Biochemistry | Base domain | AMW:CHEM:090111 |
| Basiliximab A chimeric murine-human monoclonal antibody that functions as an INTERLEUKIN 2 RECEPTOR antagonist by binding to the alpha chain (CD25 ANTIGEN) of th… | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:120818 |
| Batrachotoxins Batrachotoxin is the 20-alpha-bromobenzoate of batrachotoxin A; they are toxins from the venom of a small Colombian frog, Phyllobates aurotaenia, cau… | Complex Mixture | Biochemistry | Base domain | AMW:CHEM:200171 |
| Batroxobin A proteolytic enzyme obtained from the venom of fer-de-lance (BOTHROPS ATROX). It is used as a plasma clotting agent for fibrinogen and for the detec… | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:080688 |
| BCG Vaccine An active immunizing agent and a viable avirulent attenuated strain of MYCOBACTERIUM BOVIS, which confers immunity to mycobacterial infections. It is… | Complex Mixture | Biochemistry | Base domain | AMW:CHEM:200062 |
| bcl-2 Homologous Antagonist-Killer Protein A multi-domain mitochondrial membrane protein and member of the bcl-2 Protein family. Bak protein interacts with TUMOR SUPPRESSOR PROTEIN P53 and pro… | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:120435 |
| bcl-2-Associated X Protein A member of the Bcl-2 protein family and homologous partner of C-BCL-2 PROTO-ONCOGENE PROTEIN. It regulates the release of CYTOCHROME C and APOPTOSIS… | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:120434 |
| Bcl-2-Like Protein 11 A BCL-2-like protein that has a C-terminal BCL-2 homology (BH3) domain and forms heterodimers with other BCL-2 FAMILY PROTEINS. It is a strong induce… | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:120428 |
| bcl-Associated Death Protein A pro-apoptotic protein and member of the Bcl-2 protein family that is regulated by PHOSPHORYLATION. Unphosphorylated Bad protein inhibits the activi… | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:120433 |
| bcl-X Protein A member of the bcl-2 protein family that plays a role in the regulation of APOPTOSIS and is a regulatory subunit for PROTEIN PHOSPHATASE 1. Two majo… | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:120436 |
| Becaplermin A recombinant human platelet-derived growth factor B-chain dimer used to promote WOUND HEALING by stimulating PHYSIOLOGIC ANGIOGENESIS. | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:120305 |
| Beclin-1 An autophagy related protein which functions as a core subunit of PHOSPHATIDYLINOSITOL 3-KINASE MULTIPROTEIN COMPLEXES. It mediates the formation of … | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:120429 |
| Beclomethasone An anti-inflammatory, synthetic glucocorticoid. It is used topically as an anti-inflammatory agent and in aerosol form for the treatment of ASTHMA. | Polycyclic Compound | Biochemistry | Base domain | AMW:CHEM:040193 |
| Bee Venoms Toxins obtained from Apis mellifera (honey bee) and related species. They contain various enzymes, polypeptide toxins, and other substances, some of … | Complex Mixture | Biochemistry | Base domain | AMW:CHEM:200174 |
| Belladonna Alkaloids Alkaloids obtained from various plants, especially the deadly nightshade (Atropa belladonna), variety acuminata; atropine, hyoscyamine and scopolamin… | Heterocyclic Compound | Biochemistry | Base domain | AMW:CHEM:030150 |
| Bemegride A CNS stimulant that is used to induce convulsions in experimental animals. It has also been used as a respiratory stimulant and in the treatment of … | Heterocyclic Compound | Biochemistry | Base domain | AMW:CHEM:030533 |
| Benactyzine A centrally acting muscarinic antagonist. Benactyzine has been used in the treatment of depression and is used in research to investigate the role of… | Organic Chemical | Biochemistry | Base domain | AMW:CHEM:021041 |
| Bence Jones Protein An abnormal protein with unusual thermosolubility characteristics that is found in the urine of patients with MULTIPLE MYELOMA. | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:120904 |
| Bencyclane A vasodilator agent found to be effective in a variety of peripheral circulation disorders. It has various other potentially useful pharmacological e… | Organic Chemical | Biochemistry | Base domain | AMW:CHEM:021267 |
| Bendamustine Hydrochloride A nitrogen mustard compound that functions as an ALKYLATING ANTINEOPLASTIC AGENT and is used in the treatment of CHRONIC LYMPHOCYTIC LEUKEMIA and NON… | Organic Chemical | Biochemistry | Base domain | AMW:CHEM:020804 |
| Bendroflumethiazide A thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. It has been used in the treatment of familial hyperkalemia, hypert… | Organic Chemical | Biochemistry | Base domain | AMW:CHEM:022011 |
| Benomyl A systemic agricultural fungicide used for control of certain fungal diseases of stone fruit. | Organic Chemical | Biochemistry | Base domain | AMW:CHEM:020827 |
| Benperidol A butyrophenone with general properties similar to those of HALOPERIDOL. It has been used in the treatment of aberrant sexual behavior. (From Martind… | Organic Chemical | Biochemistry | Base domain | AMW:CHEM:021715 |
| Benserazide An inhibitor of DOPA DECARBOXYLASE that does not enter the central nervous system. It is often given with LEVODOPA in the treatment of parkinsonism t… | Organic Chemical | Biochemistry | Base domain | AMW:CHEM:021141 |
| Bentonite A colloidal, hydrated aluminum silicate that swells 12 times its dry size when added to water. | Inorganic Chemical | Biochemistry | Base domain | AMW:CHEM:010069 |
| Benz(a)Anthracenes Four fused benzyl rings with three linear and one angular, that can be viewed as a benzyl-phenanthrenes. Compare with NAPHTHACENES which are four lin… | Organic Chemical | Biochemistry | Base domain | AMW:CHEM:021458 |
| Benzaldehyde Dehydrogenase (NADP+) An NADP+ dependent enzyme that catalyzes the oxidation of benzaldehyde to BENZOIC ACID. It also plays a role in the degradation of TOLUENE and XYLENE. | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:081087 |