Public registry
Nodes
Browse canonical concepts by label, domain, node type, prefix and encoded class.
Current membership scope: Base domain only
| Concept | Node type | Base domain | Matched membership | Identifier |
|---|---|---|---|---|
| 4-Hydroxyphenylpyruvate Dioxygenase An enzyme that catalyzes the conversion of 4-hydroxyphenylpyruvate plus oxygen to homogentisic acid and carbon dioxide. EC 1.13.11.27. | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:081197 |
| 4-Nitrophenylphosphatase An enzyme that catalyzes the hydrolysis of nitrophenyl phosphates to nitrophenols. At acid pH it is probably ACID PHOSPHATASE (EC 3.1.3.2); at alkali… | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:080406 |
| 4-Nitroquinoline-1-oxide A potent mutagen and carcinogen. This compound and its metabolite 4-HYDROXYAMINOQUINOLINE-1-OXIDE bind to nucleic acids. It inactivates bacteria but … | Organic Chemical | Biochemistry | Base domain | AMW:CHEM:021821 |
| 4-Quinolones QUINOLONES containing a 4-oxo (a carbonyl in the para position to the nitrogen). They inhibit the A subunit of DNA GYRASE and are used as antimicrobi… | Heterocyclic Compound | Biochemistry | Base domain | AMW:CHEM:030917 |
| 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid An inhibitor of anion conductance including band 3-mediated anion transport. | Organic Chemical | Biochemistry | Base domain | AMW:CHEM:021335 |
| 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine A dual inhibitor of both cyclooxygenase and lipoxygenase pathways. It exerts an anti-inflammatory effect by inhibiting the formation of prostaglandin… | Heterocyclic Compound | Biochemistry | Base domain | AMW:CHEM:030250 |
| 5-alpha-Dihydroprogesterone A biologically active 5-alpha-reduced metabolite of plasma PROGESTERONE. It is the immediate precursor of 5-alpha-pregnan-3-alpha-ol-20-one (ALLOPREG… | Polycyclic Compound | Biochemistry | Base domain | AMW:CHEM:040212 |
| 5-Amino-3-((5-nitro-2-furyl)vinyl)-1,2,4-oxadiazole A nitrovinyl furan used as a schistosomicidal agent and proposed for trypanosomiasis, especially Chagas disease. | Organic Chemical | Biochemistry | Base domain | AMW:CHEM:021799 |
| 5-Aminolevulinate Synthetase An enzyme of the transferase class that catalyzes condensation of the succinyl group from succinyl coenzyme A with glycine to form delta-aminolevulin… | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:081314 |
| 5-Hydroxytryptophan The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant. | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:120042 |
| 5-Lipoxygenase-Activating Proteins Scaffolding proteins that play an important role in the localization and activation of 5-LIPOXYGENASE. | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:120929 |
| 5-Methoxypsoralen A linear furanocoumarin that has phototoxic and anti-inflammatory properties, with effects similar to METHOXSALEN. It is used in PUVA THERAPY for the… | Heterocyclic Compound | Biochemistry | Base domain | AMW:CHEM:030453 |
| 5-Methoxytryptamine Serotonin derivative proposed as potentiator for hypnotics and sedatives. | Organic Chemical | Biochemistry | Base domain | AMW:CHEM:020536 |
| 5-Methylcytosine A methylated nucleotide base found in eukaryotic DNA. In ANIMALS, the DNA METHYLATION of CYTOSINE to form 5-methylcytosine is found primarily in the … | Heterocyclic Compound | Biochemistry | Base domain | AMW:CHEM:030625 |
| 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase An enzyme that catalyzes the formation of methionine by transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine. It requires a cobam… | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:081454 |
| 5,10-Methylenetetrahydrofolate Reductase (FADH2) An FAD-dependent oxidoreductase found primarily in BACTERIA. It is specific for the reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydro… | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:081044 |
| 5,6-Dihydroxytryptamine Tryptamine substituted with two hydroxyl groups in positions 5 and 6. It is a neurotoxic serotonin analog that destroys serotonergic neurons preferen… | Heterocyclic Compound | Biochemistry | Base domain | AMW:CHEM:030753 |
| 5,7-Dihydroxytryptamine Tryptamine substituted with two hydroxyl groups in positions 5 and 7. It is a neurotoxic serotonin analog that destroys serotonergic neurons preferen… | Heterocyclic Compound | Biochemistry | Base domain | AMW:CHEM:030754 |
| 5,8,11,14-Eicosatetraynoic Acid A 20-carbon unsaturated fatty acid containing 4 alkyne bonds. It inhibits the enzymatic conversion of arachidonic acid to prostaglandins E(2) and F(2… | Lipid | Biochemistry | Base domain | AMW:CHEM:100055 |
| 5' Untranslated Regions The sequence at the 5' end of the messenger RNA that does not code for product. This sequence contains the ribosome binding site and other transcript… | Nucleic Acid Related | Biochemistry | Base domain | AMW:CHEM:130082 |
| 5'-Nucleotidase A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and… | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:080413 |
| 6-Aminonicotinamide A vitamin antagonist which has teratogenic effects. | Heterocyclic Compound | Biochemistry | Base domain | AMW:CHEM:030024 |
| 6-Cyano-7-nitroquinoxaline-2,3-dione A potent excitatory amino acid antagonist with a preference for non-NMDA iontropic receptors. It is used primarily as a research tool. | Heterocyclic Compound | Biochemistry | Base domain | AMW:CHEM:030938 |
| 6-Ketoprostaglandin F1 alpha The physiologically active and stable hydrolysis product of EPOPROSTENOL. Found in nearly all mammalian tissue. | Lipid | Biochemistry | Base domain | AMW:CHEM:100068 |
| 6-Phytase An enzyme that catalyzes the conversion of myo-inositol hexakisphosphate and water to 1L-myo-inositol 1,2,3,4,5-pentakisphosphate and orthophosphate.… | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:080432 |
| 7-Alkoxycoumarin O-Dealkylase A drug-metabolizing enzyme found in the hepatic, placental and intestinal microsomes that metabolizes 7-alkoxycoumarin to 7-hydroxycoumarin. The enzy… | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:081215 |
| 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8,8a,9a-Tetrahydrobenzo(10,11)chryseno (3,4-b)oxirene-7,8-diol. A benzopyrene derivative with carcinogenic and mutagenic activity. | Organic Chemical | Biochemistry | Base domain | AMW:CHEM:021542 |
| 8-Bromo Cyclic Adenosine Monophosphate A long-acting derivative of cyclic AMP. It is an activator of cyclic AMP-dependent protein kinase, but resistant to degradation by cyclic AMP phospho… | Heterocyclic Compound | Biochemistry | Base domain | AMW:CHEM:030841 |
| 8-Hydroxy-2-(di-n-propylamino)tetralin A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin. | Organic Chemical | Biochemistry | Base domain | AMW:CHEM:021529 |
| 8-Hydroxy-2'-Deoxyguanosine Common oxidized form of deoxyguanosine in which C-8 position of guanine base has a carbonyl group. | Heterocyclic Compound | Biochemistry | Base domain | AMW:CHEM:030816 |