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320 results

Current membership scope: Any direct membership

ConceptNode typeBase domainMatched membershipIdentifier
Erythrokeratodermia Variabilis
An autosomal dominant skin disease characterized by transient and variable noninflammatory ERYTHEMA and hyperkeratosis. It has been associated with m…
Congenital DisorderPathologyClinical Genetics [curated_secondary]AMW:DIS:160146
Familial Hypophosphatemic Rickets
A hereditary disorder characterized by HYPOPHOSPHATEMIA; RICKETS; OSTEOMALACIA; renal defects in phosphate reabsorption and vitamin D metabolism; and…
Congenital DisorderPathologyClinical Genetics [curated_secondary]AMW:DIS:050080
Familial Multiple Lipomatosis
A rare autosomal disorder characterized by numerous encapsulated lipomas on the trunk and extremities. The lipomas are usually not painful but can ca…
Congenital DisorderPathologyClinical Genetics [curated_secondary]AMW:DIS:160058
Fetus-in-Fetu
Rare abnormality where a fetal part of an identical twin that stopped developing during gestation is found within a normally developing fetus. It is …
Congenital DisorderPathologyClinical Genetics [curated_secondary]AMW:DIS:160028
Fibrous Dysplasia of Bone
A disease of bone marked by thinning of the cortex by fibrous tissue containing bony spicules, producing pain, disability, and gradually increasing d…
Pathologic ConditionPathologyClinical Genetics [curated_secondary]AMW:DIS:050045
Fibrous Dysplasia, Monostotic
FIBROUS DYSPLASIA OF BONE involving only one bone.
Pathologic ConditionPathologyClinical Genetics [curated_secondary]AMW:DIS:050048
Fibrous Dysplasia, Polyostotic
FIBROUS DYSPLASIA OF BONE affecting several bones. When melanotic pigmentation (CAFE-AU-LAIT SPOTS) and multiple endocrine hyperfunction are addition…
Pathologic ConditionPathologyClinical Genetics [curated_secondary]AMW:DIS:050049
Flatfoot
Anomaly in which one or more of the arches of the feet are flat.
Congenital DisorderPathologyClinical Genetics [curated_secondary]AMW:DIS:050156
Focal Dermal Hypoplasia
A genetic skin disease characterized by hypoplasia of the dermis, herniations of fat, and hand anomalies. It is found exclusively in females and tran…
Congenital DisorderPathologyClinical Genetics [curated_secondary]AMW:DIS:050021
Focal Facial Dermal Dysplasias
A heterogenous group of genetic disorders characterized by scar-like atrophic lesions on the temple region of the head including preauricular area. L…
Pathologic ConditionPathologyClinical Genetics [curated_secondary]AMW:DIS:160013
Foot Deformities, Congenital
Alterations or deviations from normal shape or size which result in a disfigurement of the foot occurring at or before birth.
Congenital DisorderPathologyClinical Genetics [curated_secondary]AMW:DIS:050158
Fraser Syndrome
Rare autosomal recessive congenital malformation syndrome characterized by cryptophthalmos, SYNDACTYLY and UROGENITAL ABNORMALITIES. Other anomalies …
SyndromePathologyClinical Genetics [curated_secondary]AMW:DIS:050030
Fructose Intolerance
An autosomal recessive fructose metabolism disorder due to deficient fructose-1-phosphate aldolase (EC 2.1.2.13) activity, resulting in accumulation …
Congenital DisorderPathologyClinical Genetics [curated_secondary]AMW:DIS:160086
Fructose Metabolism, Inborn Errors
Inherited abnormalities of fructose metabolism, which include three known autosomal recessive types: hepatic fructokinase deficiency (essential fruct…
Congenital DisorderPathologyClinical Genetics [curated_secondary]AMW:DIS:160084
Fructose-1,6-Diphosphatase Deficiency
An autosomal recessive fructose metabolism disorder due to absent or deficient fructose-1,6-diphosphatase activity. Gluconeogenesis is impaired, resu…
Congenital DisorderPathologyClinical Genetics [curated_secondary]AMW:DIS:160085
Funnel Chest
A developmental anomaly in which the lower sternum is posteriorly dislocated and concavely deformed, resulting in a funnel-shaped thorax.
Congenital DisorderPathologyClinical Genetics [curated_secondary]AMW:DIS:050033
Genetic Diseases, Inborn
Diseases that are caused by genetic mutations present during embryo or fetal development, although they may be observed later in life. The mutations …
Congenital DisorderPathologyClinical Genetics [curated_secondary]AMW:DIS:160056
Genetic Diseases, X-Linked
Genetic diseases that are linked to gene mutations on the X CHROMOSOME in humans (X CHROMOSOME, HUMAN) or the X CHROMOSOME in other species. Included…
Congenital DisorderPathologyClinical Genetics [curated_secondary]AMW:DIS:160059
Genetic Diseases, Y-Linked
Genetic diseases that are linked to mutant ALLELES on the Y CHROMOSOME in humans (Y CHROMOSOME, HUMAN) or the Y chromosome in other species. Included…
Congenital DisorderPathologyClinical Genetics [curated_secondary]AMW:DIS:160062
Genetic Predisposition to Disease
The concept is an etiological susceptibility/risk factor rather than a disease.
Risk FactorClinical MedicineClinical Genetics [curated_secondary]AMW:RISK:145015
Genetic Risk Score
The concept is a quantitative genetic/population parameter, not a congenital disorder.
ParameterPhysiologyClinical Genetics [curated_secondary]AMW:PARAM:210009
Genomic Instability
An increased tendency of the GENOME to acquire MUTATIONS when various processes involved in maintaining and replicating the genome are dysfunctional.
Pathologic ConditionPathologyClinical Genetics [curated_secondary]AMW:DIS:230134
Gilbert Disease
A benign familial disorder, transmitted as an autosomal dominant trait. It is characterized by low-grade chronic hyperbilirubinemia with considerable…
Congenital DisorderPathologyClinical Genetics [curated_secondary]AMW:DIS:160106
Glycogen Storage Disease
A group of inherited metabolic disorders involving the enzymes responsible for the synthesis and degradation of glycogen. In some patients, prominent…
Congenital DisorderPathologyClinical Genetics [curated_secondary]AMW:DIS:160087
Glycogen Storage Disease Type I
An autosomal recessive disease in which gene expression of glucose-6-phosphatase is absent, resulting in hypoglycemia due to lack of glucose producti…
Congenital DisorderPathologyClinical Genetics [curated_secondary]AMW:DIS:160088
Glycogen Storage Disease Type III
An autosomal recessive metabolic disorder due to deficient expression of amylo-1,6-glucosidase (one part of the glycogen debranching enzyme system). …
Congenital DisorderPathologyClinical Genetics [curated_secondary]AMW:DIS:160089
Glycogen Storage Disease Type IV
An autosomal recessive metabolic disorder due to a deficiency in expression of glycogen branching enzyme 1 (alpha-1,4-glucan-6-alpha-glucosyltransfer…
Congenital DisorderPathologyClinical Genetics [curated_secondary]AMW:DIS:160090
Glycogen Storage Disease Type V
Glycogenosis due to muscle phosphorylase deficiency. Characterized by painful cramps following sustained exercise.
Congenital DisorderPathologyClinical Genetics [curated_secondary]AMW:DIS:160091
Glycogen Storage Disease Type VI
A hepatic GLYCOGEN STORAGE DISEASE in which there is an apparent deficiency of hepatic phosphorylase (GLYCOGEN PHOSPHORYLASE, LIVER FORM) activity.
Congenital DisorderPathologyClinical Genetics [curated_secondary]AMW:DIS:160092
Glycogen Storage Disease Type VII
An autosomal recessive glycogen storage disease in which there is deficient expression of 6-phosphofructose 1-kinase in muscle (PHOSPHOFRUCTOKINASE-1…
Congenital DisorderPathologyClinical Genetics [curated_secondary]AMW:DIS:050266