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ConceptNode typeBase domainMatched membershipIdentifier
Diabetic Coma
A state of unconsciousness as a complication of diabetes mellitus. It occurs in cases of extreme HYPERGLYCEMIA or extreme HYPOGLYCEMIA as a complicat…
Metabolic DisorderPathologyEndocrinology [curated_secondary]AMW:DIS:190013
DiGeorge Syndrome
Congenital syndrome characterized by a wide spectrum of characteristics including the absence of the THYMUS and PARATHYROID GLANDS resulting in T-cel…
SyndromePathologyEndocrinology [curated_secondary]AMW:DIS:050309
Disorder of Sex Development, 46,XY
Congenital conditions in individuals with a male karyotype, in which the development of the gonadal or anatomical sex is atypical.
Congenital DisorderPathologyEndocrinology [curated_secondary]AMW:DIS:120069
Disorders of Sex Development
In gonochoristic organisms, congenital conditions in which development of chromosomal, gonadal, or anatomical sex is atypical. Effects from exposure …
Congenital DisorderPathologyEndocrinology [curated_secondary]AMW:DIS:120062
Donohue Syndrome
Rare autosomal recessive syndrome of extreme insulin resistance due to mutations in the binding domain of INSULIN RECEPTOR. Clinical features include…
SyndromePathologyEndocrinology [curated_secondary]AMW:DIS:050311
Dwarfism
A genetic or pathological condition that is characterized by short stature and undersize. Abnormal skeletal growth usually results in an adult who is…
Congenital DisorderPathologyEndocrinology [curated_secondary]AMW:DIS:050006
Dwarfism, Pituitary
A form of dwarfism caused by complete or partial GROWTH HORMONE deficiency, resulting from either the lack of GROWTH HORMONE-RELEASING FACTOR from th…
Metabolic DisorderPathologyEndocrinology [curated_secondary]AMW:DIS:050011
Dyslipidemias
Abnormalities in the serum levels of LIPIDS, including overproduction or deficiency. Abnormal serum lipid profiles may include high total CHOLESTEROL…
Metabolic DisorderPathologyEndocrinology [curated_secondary]AMW:DIS:180039
Endocrine System Diseases
Pathological processes of the ENDOCRINE GLANDS, and diseases resulting from abnormal level of available HORMONES.
Metabolic DisorderPathologyEndocrinology [curated_secondary]AMW:DIS:190001
Eunuchism
The state of being a eunuch, a male without TESTES or whose testes failed to develop. It is characterized by the lack of mature male GERM CELLS and T…
Metabolic DisorderPathologyEndocrinology [curated_secondary]AMW:DIS:190017
Euthyroid Sick Syndromes
Conditions of abnormal THYROID HORMONES release in patients with apparently normal THYROID GLAND during severe systemic illness, physical TRAUMA, and…
SyndromePathologyEndocrinology [curated_secondary]AMW:DIS:190027
Familial Hypophosphatemic Rickets
A hereditary disorder characterized by HYPOPHOSPHATEMIA; RICKETS; OSTEOMALACIA; renal defects in phosphate reabsorption and vitamin D metabolism; and…
Congenital DisorderPathologyEndocrinology [curated_secondary]AMW:DIS:050080
Gigantism
The condition of accelerated and excessive GROWTH in children or adolescents who are exposed to excess HUMAN GROWTH HORMONE before the closure of EPI…
Metabolic DisorderPathologyEndocrinology [curated_secondary]AMW:DIS:050034
Glucose Intolerance
A pathological state in which BLOOD GLUCOSE level is less than approximately 140 mg/100 ml of PLASMA at fasting, and above approximately 200 mg/100 m…
Metabolic DisorderPathologyEndocrinology [curated_secondary]AMW:DIS:180027
Glucose Metabolism Disorders
Pathological conditions in which the BLOOD GLUCOSE cannot be maintained within the normal range, such as in HYPOGLYCEMIA and HYPERGLYCEMIA. Etiology …
Metabolic DisorderPathologyEndocrinology [curated_secondary]AMW:DIS:180018
Goiter
Enlargement of the THYROID GLAND that may increase from about 20 grams to hundreds of grams in human adults. Goiter is observed in individuals with n…
Metabolic DisorderPathologyEndocrinology [curated_secondary]AMW:DIS:190028
Goiter, Endemic
A form of IODINE deficiency disorders characterized by an enlargement of the THYROID GLAND in a significantly large fraction of a POPULATION GROUP. E…
Metabolic DisorderPathologyEndocrinology [curated_secondary]AMW:DIS:190029
Goiter, Nodular
An enlarged THYROID GLAND containing multiple nodules (THYROID NODULE), usually resulting from recurrent thyroid HYPERPLASIA and involution over many…
Metabolic DisorderPathologyEndocrinology [curated_secondary]AMW:DIS:190030
Goiter, Substernal
An enlarged THYROID GLAND with at least 50% of the gland situated behind the STERNUM. It is an unusual presentation of an intrathoracic goiter. Subst…
Metabolic DisorderPathologyEndocrinology [curated_secondary]AMW:DIS:190031
Gonadal Disorders
Pathological processes of the OVARIES or the TESTES.
Metabolic DisorderPathologyEndocrinology [curated_secondary]AMW:DIS:190015
Gonadal Dysgenesis
A number of syndromes with defective gonadal developments such as streak GONADS and dysgenetic testes or ovaries. The spectrum of gonadal and sexual …
Congenital DisorderPathologyEndocrinology [curated_secondary]AMW:DIS:120074
Gonadal Dysgenesis, 46,XX
The 46,XX gonadal dysgenesis may be sporadic or familial. Familial XX gonadal dysgenesis is transmitted as an autosomal recessive trait and its locus…
Congenital DisorderPathologyEndocrinology [curated_secondary]AMW:DIS:120065
Gonadal Dysgenesis, 46,XY
Defects in the SEX DETERMINATION PROCESS in 46, XY individuals that result in abnormal gonadal development and deficiencies in TESTOSTERONE and subse…
Congenital DisorderPathologyEndocrinology [curated_secondary]AMW:DIS:120072
Gonadal Dysgenesis, Mixed
A type of defective gonadal development in patients with a wide spectrum of chromosomal mosaic variants. Their karyotypes are of partial sex chromoso…
Congenital DisorderPathologyEndocrinology [curated_secondary]AMW:DIS:120075
Hashimoto Disease
Chronic autoimmune thyroiditis, characterized by the presence of high serum thyroid AUTOANTIBODIES; GOITER; and HYPOTHYROIDISM.
Metabolic DisorderPathologyEndocrinology [curated_secondary]AMW:DIS:190040
Hyperaldosteronism
A condition caused by the overproduction of ALDOSTERONE. It is characterized by sodium retention and potassium excretion with resultant HYPERTENSION …
Metabolic DisorderPathologyEndocrinology [curated_secondary]AMW:DIS:190010
Hyperandrogenism
A condition caused by the excessive secretion of ANDROGENS from the ADRENAL CORTEX; the OVARIES; or the TESTES. The clinical significance in males is…
Congenital DisorderPathologyEndocrinology [curated_secondary]AMW:DIS:120066
Hypercholesterolemia
A condition with abnormally high levels of CHOLESTEROL in the blood. It is defined as a cholesterol value exceeding the 95th percentile for the popul…
Metabolic DisorderPathologyEndocrinology [curated_secondary]AMW:DIS:180041
Hyperglycemia
Abnormally high BLOOD GLUCOSE level.
Metabolic DisorderPathologyEndocrinology [curated_secondary]AMW:DIS:180026
Hyperglycemic Hyperosmolar Nonketotic Coma
A serious complication of TYPE 2 DIABETES MELLITUS. It is characterized by extreme HYPERGLYCEMIA; DEHYDRATION; serum hyperosmolarity; and depressed c…
Metabolic DisorderPathologyEndocrinology [curated_secondary]AMW:DIS:190014