Nodes

Any method used for determining the location of and relative distances between genes on a chromosome.

The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, …

The formation of one or more genetically identical organisms derived by vegetative reproduction from a single cell. The source nuclear material can b…

A technique of culturing mixed cell types in vitro to allow their synergistic or antagonistic interactions, such as on CELL DIFFERENTIATION or APOPTO…

A method for comparing two sets of chromosomal DNA by analyzing differences in the copy number and location of specific sequences. It is used to look…

Composite renal function parameter used in organ dysfunction scoring, combining serum creatinine thresholds and urine output thresholds.

Deliberate breeding of two different individuals that results in offspring that carry part of the genetic material of each parent. The parent organis…

The formation of crystalline substances from solutions or melts. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)

The branch of science that deals with the geometric description of crystals and their internal arrangement. (McGraw-Hill Dictionary of Scientific and…

The study of crystal structure using X-RAY DIFFRACTION techniques. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)

Primarily a pathological, laboratory or structured observational finding rather than a disease entity.

Methods of maintaining or growing biological materials in controlled laboratory conditions. These include the cultures of CELLS; TISSUES; organs; or …

Diagnosis of the type and, when feasible, the cause of a pathologic process by means of microscopic study of cells in an exudate or other form of bod…

Methods used to study CELLS.

Visible morphologic changes in cells infected with viruses. It includes shutdown of cellular RNA and protein synthesis, cell fusion, release of lysos…

Removal of minerals from bones during bone examination.

A research technique to measure solvent exposed regions of molecules that is used to provide insight about PROTEIN CONFORMATION.

The techniques used to produce molecules exhibiting properties that conform to the demands of the experimenter. These techniques combine methods of g…

Techniques for standardizing and expediting taxonomic identification or classification of organisms that are based on deciphering the sequence of one…

A technique for identifying individuals of a species that is based on the uniqueness of their DNA sequence. Uniqueness is determined by identifying w…

A method for determining the sequence specificity of DNA-binding proteins. DNA footprinting utilizes a DNA damaging agent (either a chemical reagent …

Biochemical identification of mutational changes in a nucleotide sequence.

The use of DNA recombination (RECOMBINATION, GENETIC) to prepare a large gene library of novel, chimeric genes from a population of randomly fragment…

A technique in which electric pulses, in kilovolts per centimeter and of microsecond-to-millisecond duration, cause a loss of the semipermeability of…

The technique of maintaining or growing mammalian EMBRYOS in vitro. This method offers an opportunity to observe EMBRYONIC DEVELOPMENT; METABOLISM; a…

Utilization or disposal of an embryo that is fertilized but not immediately transplanted and resulting course of action.

A genetic engineering technique that involves manipulating the EPIGENOME at the target region with minimal or no modification of the genomic DNA.

Techniques used to determine the sequences of EXONS of an organism or individual.

Technique using an instrument system for making, processing, and displaying one or more measurements on individual cells obtained from a cell suspens…

A method used to study the lateral movement of MEMBRANE PROTEINS and LIPIDS. A small area of a cell membrane is bleached by laser light and the amoun…