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Primarily a pathological, laboratory or structured observational finding rather than a disease entity.

Methods of maintaining or growing biological materials in controlled laboratory conditions. These include the cultures of CELLS; TISSUES; organs; or …

Synthetic organic reactions that use reactions between unsaturated molecules to form cyclical products.

Diagnosis of the type and, when feasible, the cause of a pathologic process by means of microscopic study of cells in an exudate or other form of bod…

Examination of CHROMOSOMES to diagnose, classify, screen for, or manage genetic diseases and abnormalities. Following preparation of the sample, KARY…

Methods used to study CELLS.

Visible morphologic changes in cells infected with viruses. It includes shutdown of cellular RNA and protein synthesis, cell fusion, release of lysos…

The demonstration of the cytotoxic effect on a target cell of a lymphocyte, a mediator released by a sensitized lymphocyte, an antibody, or complemen…

A measure of scientific precision, exactness, or correctness of quantitative or qualitative values, relative to the actual or true measurements.

Removal of minerals from bones during bone examination.

Electrophoresis in which various denaturant gradients are used to induce nucleic acids to melt at various stages resulting in separation of molecules…

Removal of moisture from a substance (chemical, food, tissue, etc.).

A research technique to measure solvent exposed regions of molecules that is used to provide insight about PROTEIN CONFORMATION.

The process of gaining approval by a government regulatory agency for DIAGNOSTIC REAGENTS AND TEST KITS. This includes any required preclinical or cl…

Diagnostic procedures, such as laboratory tests and x-rays, routinely performed on all individuals or specified categories of individuals in a specif…

A process of selective diffusion through a membrane. It is usually used to separate low-molecular-weight solutes which diffuse through the membrane f…

A technique of measuring the dielectric properties of materials, which vary over a range of frequencies depending on the physical properties of the m…

Technique by which phase transitions of chemical reactions can be followed by observation of the heat absorbed or liberated.

The closeness of a determined value of a physical dimension to the actual value.

The techniques used to produce molecules exhibiting properties that conform to the demands of the experimenter. These techniques combine methods of g…

A method where a culturing surface inoculated with microbe is exposed to small disks containing known amounts of a chemical agent resulting in a zone…

The separation and isolation of tissues for surgical purposes, or for the analysis or study of their structures.

A chemical process for separating the components of a liquid mixture by boiling and collecting condensed vapors.

Techniques for standardizing and expediting taxonomic identification or classification of organisms that are based on deciphering the sequence of one…

The presence of DNA from a source foreign to the sample being analysed.

A technique for identifying individuals of a species that is based on the uniqueness of their DNA sequence. Uniqueness is determined by identifying w…

A method for determining the sequence specificity of DNA-binding proteins. DNA footprinting utilizes a DNA damaging agent (either a chemical reagent …

Biochemical identification of mutational changes in a nucleotide sequence.

The use of DNA recombination (RECOMBINATION, GENETIC) to prepare a large gene library of novel, chimeric genes from a population of randomly fragment…

Techniques for using whole blood samples collected on filter paper for a variety of clinical laboratory tests.