Public registry
Nodes
Browse canonical concepts by label, domain, node type, prefix and encoded class.
Current membership scope: Secondary membership only
| Concept | Node type | Base domain | Matched membership | Identifier |
|---|---|---|---|---|
| Synesthesia The experience of involuntary sensory cross activation where the presentation of a particular stimulus elicits a secondary sensory-perceptual experie… | Disorder | Pathology | Nervous System [curated_secondary] | AMW:DIS:100515 |
| Synkinesis An involuntary movement accompanying a volitional movement. It often refers to facial movements that accompany FACIAL PARALYSIS. | Pathologic Condition | Pathology | Nervous System [curated_secondary] | AMW:DIS:100444 |
| Synucleinopathies Neurodegenerative disorders involving deposition of abnormal ALPHA-SYNUCLEIN in dopaminergic neurons and glial cells in the brain. Pathological aggre… | Metabolic Disorder | Pathology | Nervous System [curated_secondary] | AMW:DIS:100421 |
| Syringomyelia Longitudinal cavities in the spinal cord, most often in the cervical region, which may extend for multiple spinal levels. The cavities are lined by d… | Disorder | Pathology | Nervous System [curated_secondary] | AMW:DIS:100330 |
| Tangier Disease An autosomal recessively inherited disorder caused by mutation of ATP-BINDING CASSETTE TRANSPORTERS involved in cellular cholesterol removal (reverse… | Congenital Disorder | Pathology | Nervous System [curated_secondary] | AMW:DIS:100615 |
| Tardive Dyskinesia Drug-related movement disorder characterized by uncontrollable movements in certain muscles. It is associated with a long-term exposure to certain ne… | Pathologic Condition | Pathology | Nervous System [curated_secondary] | AMW:DIS:100312 |
| Tarsal Tunnel Syndrome Entrapment of the distal branches of the posterior TIBIAL NERVE (which divides into the medial plantar, lateral plantar, and calcanial nerves) in the… | Syndrome | Pathology | Nervous System [curated_secondary] | AMW:DIS:100597 |
| Taste Disorders Conditions characterized by an alteration in gustatory function or perception. Taste disorders are frequently associated with OLFACTION DISORDERS. Ad… | Pathologic Condition | Pathology | Nervous System [curated_secondary] | AMW:DIS:100562 |
| Tauopathies Neurodegenerative disorders involving deposition of abnormal tau protein isoforms (TAU PROTEINS) in neurons and glial cells in the brain. Pathologica… | Disorder | Pathology | Nervous System [curated_secondary] | AMW:DIS:100422 |
| Tay-Sachs Disease An autosomal recessive neurodegenerative disorder characterized by the onset in infancy of an exaggerated startle response, followed by paralysis, de… | Congenital Disorder | Pathology | Nervous System [curated_secondary] | AMW:DIS:100102 |
| Tay-Sachs Disease, AB Variant A progressive neurodegenerative disorder that begins with muscle weakness, then progresses to startle reaction, retardation and seizures. It is chara… | Congenital Disorder | Pathology | Nervous System [curated_secondary] | AMW:DIS:100103 |
| TDP-43 Proteinopathies Diseases characterized by the presence of abnormally phosphorylated, ubiquitinated, and cleaved DNA-binding protein TDP-43 in affected brain and spin… | Metabolic Disorder | Pathology | Nervous System [curated_secondary] | AMW:DIS:100424 |
| Tetany A disorder characterized by muscle twitches, cramps, and carpopedal spasm, and when severe, laryngospasm and seizures. This condition is associated w… | Metabolic Disorder | Pathology | Nervous System [curated_secondary] | AMW:DIS:100531 |
| Thalamic Diseases Disorders of the centrally located thalamus, which integrates a wide range of cortical and subcortical information. Manifestations include sensory lo… | Disorder | Pathology | Nervous System [curated_secondary] | AMW:DIS:100302 |
| Thoracic Outlet Syndrome A neurovascular syndrome associated with compression of the BRACHIAL PLEXUS; SUBCLAVIAN ARTERY; and SUBCLAVIAN VEIN at the superior thoracic outlet. … | Syndrome | Pathology | Nervous System [curated_secondary] | AMW:DIS:100604 |
| Thrombotic Stroke A type of ischemic stroke resulting from obstruction due to a BLOOD CLOT formed within in a CEREBRAL ARTERY often associated with ATHEROSCLEROSIS. A … | Vascular Disorder | Pathology | Nervous System [curated_secondary] | AMW:DIS:100222 |
| Tibial Neuropathy Disease of the TIBIAL NERVE (also referred to as the posterior tibial nerve). The most commonly associated condition is the TARSAL TUNNEL SYNDROME. H… | Disorder | Pathology | Nervous System [curated_secondary] | AMW:DIS:100596 |
| Tics Habitual, repeated, rapid contraction of certain muscles, resulting in stereotyped individualized actions that can be voluntarily suppressed for only… | Pathologic Condition | Pathology | Nervous System [curated_secondary] | AMW:DIS:100445 |
| Tolosa-Hunt Syndrome An idiopathic syndrome characterized by the formation of granulation tissue in the anterior cavernous sinus or superior orbital fissure, producing a … | Syndrome | Pathology | Nervous System [curated_secondary] | AMW:DIS:100151 |
| Tonic Pupil A pupillary abnormality characterized by a poor pupillary light reaction, reduced accommodation, iris sector palsies, an enhanced pupillary response … | Pathologic Condition | Pathology | Nervous System [curated_secondary] | AMW:DIS:100546 |
| Torticollis A symptom, not a disease, of a twisted neck. In most instances, the head is tipped toward one side and the chin rotated toward the other. The involun… | Pathologic Condition | Pathology | Nervous System [curated_secondary] | AMW:DIS:230260 |
| Toxic Metabolic Encephalopathy Toxic metabolic encephalopathy used as a ClinicalGraph target concept for pathology / differential. | Disorder | Pathology | Nervous System [curated_secondary] | AMW:DIS:100677 |
| Toxic Optic Neuropathy Damage to the eye or its function (e.g., VISUAL IMPAIRMENT) due to OPTIC NERVE damage secondary to toxic substances such as drugs used in CHEMOTHERAP… | Pathologic Condition | Pathology | Nervous System [curated_secondary] | AMW:DIS:100346 |
| Trauma, Nervous System Traumatic injuries to the brain, cranial nerves, spinal cord, autonomic nervous system, or neuromuscular system, including iatrogenic injuries induce… | Traumatic Disorder | Pathology | Nervous System [curated_secondary] | AMW:DIS:100650 |
| Tremor Primarily an observable or examinable clinical manifestation rather than a disease entity. | Clinical Sign | Clinical Medicine | Nervous System [curated_secondary] | AMW:SIGN:145029 |
| Trigeminal Autonomic Cephalalgias Primary headache disorders that show symptoms caused by the activation of the AUTONOMIC NERVOUS SYSTEM of the TRIGEMINAL NERVE. These autonomic featu… | Disorder | Pathology | Nervous System [curated_secondary] | AMW:DIS:100272 |
| Trismus Spasmodic contraction of the masseter muscle resulting in forceful jaw closure. This may be seen with a variety of diseases, including TETANUS, as a … | Pathologic Condition | Pathology | Nervous System [curated_secondary] | AMW:DIS:100530 |
| Trisomy 13 Syndrome A chromosome disorder associated with TRISOMY of all or part of CHROMOSOME 13. Clinical manifestations include CONGENITAL HEART DEFECTS (e.g., PATENT… | Syndrome | Pathology | Nervous System [curated_secondary] | AMW:DIS:100496 |
| Trochlear Nerve Diseases Diseases of the fourth cranial (trochlear) nerve or its nucleus in the midbrain. The nerve crosses as it exits the midbrain dorsally and may be injur… | Disorder | Pathology | Nervous System [curated_secondary] | AMW:DIS:100372 |
| Trochlear Nerve Injuries Traumatic injuries to the TROCHLEAR NERVE. | Traumatic Disorder | Pathology | Nervous System [curated_secondary] | AMW:DIS:100347 |