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Browse canonical concepts by label, domain, node type, prefix and encoded class.

2,167 results

Current membership scope: Base domain only

ConceptNode typeBase domainMatched membershipIdentifier
Genes, MHC Class I
Genetic loci in the vertebrate major histocompatibility complex which encode polymorphic characteristics not related to immune responsiveness or comp…
ConceptPhysiologyBase domainAMW:PHYS:050281
Genes, MHC Class II
Genetic loci in the vertebrate major histocompatibility complex that encode polymorphic products which control the immune response to specific antige…
ConceptPhysiologyBase domainAMW:PHYS:050282
Genes, Microbial
The functional hereditary units of a microorganism.
ConceptPhysiologyBase domainAMW:PHYS:050210
Genes, Mitochondrial
Genes that are located on the MITOCHONDRIAL DNA. Mitochondrial inheritance is often referred to as maternal inheritance but should be differentiated …
ConceptPhysiologyBase domainAMW:PHYS:050226
Genes, Modifier
GENES with ALLELES that affect the PHENOTYPE associated with a nonallelic gene.
ConceptPhysiologyBase domainAMW:PHYS:050227
Genes, mos
Retrovirus-associated DNA sequences (mos) originally isolated from the Moloney murine sarcoma virus (Mo-MSV). The proto-oncogene mos (c-mos) codes fo…
ConceptPhysiologyBase domainAMW:PHYS:050253
Genes, myb
Retrovirus-associated DNA sequences (v-myb) originally isolated from the avian myeloblastosis and E26 leukemia viruses. The proto-oncogene c-myb code…
ConceptPhysiologyBase domainAMW:PHYS:050254
Genes, myc
Family of retrovirus-associated DNA sequences (myc) originally isolated from an avian myelocytomatosis virus. The proto-oncogene myc (c-myc) codes fo…
ConceptPhysiologyBase domainAMW:PHYS:050255
Genes, nef
DNA sequences that form the coding region for a protein that down-regulates the expression of human immunodeficiency virus (HIV). nef is short for ne…
ConceptPhysiologyBase domainAMW:PHYS:050218
Genes, Neoplasm
Genes whose abnormal expression, or MUTATION are associated with the development, growth, or progression of NEOPLASMS.
ConceptPhysiologyBase domainAMW:PHYS:050228
Genes, Neurofibromatosis 1
Tumor suppressor genes located on the long arm of human chromosome 17 in the region 17q11.2. Mutation of these genes is thought to cause NEUROFIBROMA…
ConceptPhysiologyBase domainAMW:PHYS:050235
Genes, Neurofibromatosis 2
Tumor suppressor genes located on the long arm of human chromosome 22. Mutation or loss of these genes causes NEUROFIBROMATOSIS 2.
ConceptPhysiologyBase domainAMW:PHYS:050236
Genes, Overlapping
Genes whose nucleotide sequences overlap to some degree. The overlapped sequences may involve structural or regulatory genes of eukaryotic or prokary…
ConceptPhysiologyBase domainAMW:PHYS:050260
Genes, p16
Tumor suppressor genes located on human chromosome 9 in the region 9p21. This gene is either deleted or mutated in a wide range of malignancies. (Fro…
ConceptPhysiologyBase domainAMW:PHYS:050237
Genes, p53
Tumor suppressor genes located on the short arm of human chromosome 17 and coding for the phosphoprotein p53.
ConceptPhysiologyBase domainAMW:PHYS:050238
Genes, Plant
The functional hereditary units of PLANTS.
ConceptPhysiologyBase domainAMW:PHYS:050262
Genes, pol
DNA sequences that form the coding region for retroviral enzymes including reverse transcriptase, protease, and endonuclease/integrase. pol is short …
ConceptPhysiologyBase domainAMW:PHYS:050219
Genes, Protozoan
The functional hereditary units of protozoa.
ConceptPhysiologyBase domainAMW:PHYS:050263
Genes, pX
DNA sequences that form the coding region for at least three proteins which regulate the expression of HUMAN T-LYMPHOTROPIC VIRUS 1 and HUMAN T-LYMPH…
ConceptPhysiologyBase domainAMW:PHYS:050220
Genes, RAG-1
Genes involved in activating the enzyme VDJ recombinase. RAG-1 is located on chromosome 11 in humans (chromosome 2 in mice) and is expressed exclusiv…
ConceptPhysiologyBase domainAMW:PHYS:050264
Genes, ras
Family of retrovirus-associated DNA sequences (ras) originally isolated from Harvey (H-ras, Ha-ras, rasH) and Kirsten (K-ras, Ki-ras, rasK) murine sa…
ConceptPhysiologyBase domainAMW:PHYS:050256
Genes, Recessive
Genes that influence the PHENOTYPE only in the homozygous state.
ConceptPhysiologyBase domainAMW:PHYS:050265
Genes, Regulator
Genes which regulate or circumscribe the activity of other genes; specifically, genes which code for PROTEINS or RNAs which have GENE EXPRESSION REGU…
ConceptPhysiologyBase domainAMW:PHYS:050266
Genes, rel
Family of retrovirus-associated DNA sequences (v-rel) originally isolated from an avian reticuloendotheliosis virus strain. The proto-oncogene rel (c…
ConceptPhysiologyBase domainAMW:PHYS:050257
Genes, Reporter
Genes whose expression is easily detectable and therefore used to study promoter activity at many positions in a target genome. In recombinant DNA te…
ConceptPhysiologyBase domainAMW:PHYS:050269
Genes, Retinoblastoma
Tumor suppressor genes located on human chromosome 13 in the region 13q14 and coding for a family of phosphoproteins with molecular weights ranging f…
ConceptPhysiologyBase domainAMW:PHYS:050239
Genes, rev
DNA sequences that form the coding region for a protein that regulates the expression of the viral structural and regulatory proteins in human immuno…
ConceptPhysiologyBase domainAMW:PHYS:050221
Genes, sis
Retrovirus-associated DNA sequences (v-sis) originally isolated from the simian sarcoma virus (SSV). The proto-oncogene c-sis codes for a growth fact…
ConceptPhysiologyBase domainAMW:PHYS:050258
Genes, src
Retrovirus-associated DNA sequences (src) originally isolated from the Rous sarcoma virus (RSV). The proto-oncogene src (c-src) codes for a protein t…
ConceptPhysiologyBase domainAMW:PHYS:050259
Genes, sry
The primary testis-determining gene in mammalians, located on the Y CHROMOSOME. It codes for a high mobility group box transcription factor (TRANSCRI…
ConceptPhysiologyBase domainAMW:PHYS:050270