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Expected weight of a healthy normal individual based on age, sex, and height. Thus, a malnourished person would weigh less than their ideal body weig…

An induced response to threatening stimuli characterized by complete loss of muscle strength.

Methods used by pathogenic organisms to evade a host's immune system.

Phenomenon which occurs in certain tissue sites and organs (e.g., the ANTERIOR CHAMBER and CORNEA of the eye, brain PARENCHYMAL TISSUE and fetus) to …

Regeneration of normal immune function after immune depleting procedures or infections (e.g., HEMATOPOIETIC STEM CELL TRANSPLANTATION). Delayed and i…

A spectrum of functional deterioration in various lymphocyte populations that is induced by continuous antigenic stimulation. There are overlapping s…

The characteristic properties and processes involved in IMMUNITY and an organism's immune response.

The specific failure of a normally responsive individual to make an immune response to a known antigen. It results from previous contact with the ant…

Nonsusceptibility to the invasive or pathogenic effects of foreign microorganisms or to the toxic effect of antigenic substances.

Resistance to a disease agent resulting from the production of specific antibodies by the host, either after exposure to the disease or after vaccina…

Manifestations of the immune response which are mediated by antigen-sensitized T-lymphocytes via lymphokines or direct cytotoxicity. This takes place…

The state of a community in which a significant proportion of its population becomes immune to an infectious disease, and the risk of person-to-perso…

The immunological phenomenon by which exposure to some organisms or vaccines can profoundly alter the host's response to subsequent exposure to unrel…

Antibody-mediated immune response. Humoral immunity is brought about by ANTIBODY FORMATION, resulting from TH2 CELLS activating B-LYMPHOCYTES, follow…

The capacity of a normal organism to remain unaffected by microorganisms and their toxins. It results from the presence of naturally occurring ANTI-I…

Resistance to a disease-causing agent induced by the introduction of maternal immunity into the fetus by transplacental transfer or into the neonate …

Nonsusceptibility to the pathogenic effects of foreign microorganisms or antigenic substances as a result of antibody secretions of the mucous membra…

The ability of lymphoid cells to mount a humoral or cellular immune response when challenged by antigen.

A human or animal whose immunologic mechanism is deficient because of an immunodeficiency disorder or other disease or as the result of the administr…

The reduction of the immunogenicity of a population of tumor cells over time, under the GENETIC SELECTION pressure of IMMUNOLOGIC SURVEILLANCE, leadi…

GENETIC PHENOMENA and processes involved in IMMUNITY and the immune response.

A form of regulated cell death that results in release of specific DAMAGE ASSOCIATED MOLECULAR PATTERN MOLECULES which activate an ADAPTIVE IMMUNE RE…

The capacity of VACCINES to stimulate the ADAPTIVE IMMUNE RESPONSE to produce antibodies and antigen-specific T-CELL responses. It is typically measu…

Gene rearrangement of the B-lymphocyte which results in a substitution in the type of heavy-chain constant region that is expressed. This allows the …

Compact globular protein domains of about 80 to 110 amino acids.They are characterized by two antiparallel beta sheets stabilized by HYDROPHOBIC INTE…

A site located in the INTRONS at the 5' end of each constant region segment of a immunoglobulin heavy-chain gene where recombination (or rearrangemen…

An energy dependent process following the crosslinking of B CELL ANTIGEN RECEPTORS by multivalent ligands (bivalent anti-antibodies, LECTINS or ANTIG…

The altered state of immunologic responsiveness resulting from initial contact with antigen, which enables the individual to produce antibodies more …

The theory that T-cells monitor cell surfaces and detect structural changes in the plasma membrane and/or surface antigens of virally or neoplastical…

Diets supplemented with nutrients that beneficially stimulate the IMMUNE RESPONSE and improve control of inflammatory processes.