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Investigative techniques used in pre-clinical and clinical research, epidemiology, chemistry, immunology, genetics, etc. They do not include techniqu…

A nonparametric method of compiling LIFE TABLES or survival tables. It combines calculated probabilities of survival and estimates to allow for obser…

Computational designs that apply DEEP LEARNING methods on extremely large data sets as a basis for predicting and constructing natural-sounding text.

A statistical algorithm used to analyze clusters of observed variables by constructing categorical unobserved or latent segment based on weighted ana…

A principle of estimation in which the estimates of a set of parameters in a statistical model are those quantities minimizing the sum of squared dif…

The dose amount of poisonous or toxic substance or dose of ionizing radiation required to kill 50% of the tested population.

Leukemia induced experimentally in animals by exposure to leukemogenic agents, such as VIRUSES; RADIATION; or by TRANSPLANTATION of leukemic tissues.

Functions constructed from a statistical model and a set of observed data which give the probability of that data for various values of the unknown m…

Statistical models in which the value of a parameter for a given value of a factor is assumed to be equal to a + bx, where a and b are constants. The…

Experimentally induced chronic injuries to the parenchymal cells in the liver to achieve a model for LIVER CIRRHOSIS.

Experimentally induced tumors of the LIVER.

Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values…

Studies in which variables relating to an individual or group of individuals are assessed over a period of time.

The application of LUBRICANTS to diminish FRICTION between two surfaces.

Experimentally induced mammary neoplasms in animals to provide a model for studying human BREAST NEOPLASMS.

A stochastic process such that the conditional probability distribution for a state at any future instant, given the present state, is unaffected by …

A type of analysis in which subjects in a study group and a comparison group are made comparable with respect to extraneous factors by individually p…

The highest dose of a biologically active agent given during a chronic study that will not reduce longevity from effects other than carcinogenicity. …

A type of statistical analysis used to understand, clarify, and explain the relationship and pathway between a presumed cause (an independent variabl…

Experimentally induced tumor that produces MELANIN in animals to provide a model for studying human MELANOMA.

The use of the GENETIC VARIATION of known functions or phenotypes to correlate the causal effects of those functions or phenotypes with a disease out…

A quantitative method of combining the results of independent studies (usually drawn from the published literature) and synthesizing summaries and co…

Methods and techniques used to genetically modify cells' biosynthetic product output and develop conditions for growing the cells as BIOREACTORS.

A series of steps taken in order to conduct research.

Induction and quantitative measurement of chromosomal damage leading to the formation of micronuclei (MICRONUCLEI, CHROMOSOME-DEFECTIVE) in cells whi…

Non-human animals, selected because of specific characteristics, for use in experimental research, teaching, or testing.

Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE…

A systematic integration of biological, psychological, and social approaches to the study of mental health and specific mental disorders.

Theoretical representations that simulate the behavior or activity of the cardiovascular system, processes, or phenomena; includes the use of mathema…

Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, co…