Inorganic Chemical

Cisplatin

AMW:CHEM:010108

An inorganic and water-soluble platinum complex. After undergoing hydrolysis, it reacts with DNA to produce both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity of cisplatin correlates with cellular arrest in the G2 phase of the cell cycle.

Biochemistry chemical

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Graph assertions

Cisplatin has parent Chlorine Compounds

Cisplatin has parent Nitrogen Compounds

Cisplatin has parent Platinum Compounds

Cisplatin member of drug class Platinum Complexes

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Identifier classification

PrefixChemical substances · AMW:CHEM:

Class01 · Inorganic Chemicals

Domains

Biochemistry · base Pharmacology · base

Semantic roles

Biochemistry / Concept Pharmacology / Drug

Public labels

Cisplatin en · preferred