Heterocyclic Compound

Irinotecan

AMW:CHEM:030055

A semisynthetic camptothecin derivative that inhibits DNA TOPOISOMERASE I to prevent nucleic acid synthesis during S PHASE. It is used as an antineoplastic agent for the treatment of COLORECTAL NEOPLASMS and PANCREATIC NEOPLASMS.

Biochemistry chemical

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Graph assertions

Irinotecan has parent Camptothecin

Irinotecan member of drug class Topoisomerase I Inhibitors

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Identifier classification

PrefixChemical substances · AMW:CHEM:

Class03 · Heterocyclic Compounds

Domains

Biochemistry · base Pharmacology · base

Semantic roles

Biochemistry / Concept Pharmacology / Drug

Public labels

Irinotecan en · preferred