Enzyme or Coenzyme

Immunophilins

AMW:CHEM:080745

Members of a family of highly conserved proteins which are all cis-trans peptidyl-prolyl isomerases (PEPTIDYLPROLYL ISOMERASE). They bind the immunosuppressant drugs CYCLOSPORINE; TACROLIMUS and SIROLIMUS. They possess rotamase activity, which is inhibited by the immunosuppressant drugs that bind to them.

Biochemistry biochemical

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Cyclophilins has parent Immunophilins

Tacrolimus Binding Proteins has parent Immunophilins

Immunophilins has parent Peptidylprolyl Isomerase

Immunophilins has parent Receptors, Drug

Immunophilins has parent Receptors, Immunologic

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