Enzyme or Coenzyme

AlkB Homolog 4, Lysine Demethylase

AMW:CHEM:081135

A dioxygenase and alkylation repair homolog that mediates demethylation of ACTIN monomethylated at 'Lys-84' (K84me1). Demethylation of actin LYSINE 84 (K84me1) is required for maintaining actin and MYOSIN dynamics to support normal cleavage furrow ingression during CYTOKINESIS and CELL MIGRATION. It may also be involved in transcription regulation.

Biochemistry biochemical

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AlkB Homolog 4, Lysine Demethylase has parent AlkB Enzymes

AlkB Homolog 4, Lysine Demethylase has parent Oxidoreductases, N-Demethylating

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