Enzyme or Coenzyme
2',5'-Oligoadenylate Synthetase
AMW:CHEM:081495An enzyme that catalyzes the conversion of ATP into a series of (2'-5') linked oligoadenylates and pyrophosphate in the presence of double-stranded RNA. These oligonucleotides activate an endoribonuclease (RNase L) which cleaves single-stranded RNA. Interferons can act as inducers of these reactions.
Biochemistry
biochemical