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Peptide or Protein

STAT Transcription Factors

AMW:CHEM:120409

A family of transcription factors containing SH2 DOMAINS that are involved in CYTOKINE-mediated SIGNAL TRANSDUCTION. STAT transcription factors are recruited to the cytoplasmic region of CELL SURFACE RECEPTORS and are activated via PHOSPHORYLATION. Once activated they dimerize and translocate into the CELL NUCLEUS where they influence GENE expression. They play a role in regulating CELL GROWTH PROCESSES and CELL DIFFERENTIATION. STAT transcription factors are inhibited by SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS and PROTEIN INHIBITORS OF ACTIVATED STAT.

Biochemistry biochemical
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STAT Transcription Factors has parent Adaptor Proteins, Signal Transducing
STAT1 Transcription Factor has parent STAT Transcription Factors
STAT2 Transcription Factor has parent STAT Transcription Factors
STAT3 Transcription Factor has parent STAT Transcription Factors
STAT4 Transcription Factor has parent STAT Transcription Factors
STAT5 Transcription Factor has parent STAT Transcription Factors
STAT6 Transcription Factor has parent STAT Transcription Factors
STAT Transcription Factors has parent Transcription Factors

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