Peptide or Protein

Abciximab

AMW:CHEM:120582

A Fab fragment of the chimeric monoclonal antibody 7E3 that binds to the glycoprotein IIb-IIIa receptor of human platelets, and blocks PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX, potently inhibiting PLATELET AGGREGATION. It is used in treatment of refractory unstable angina, and for prevention of ischemic complications in patients undergoing percutaneous coronary procedures such as ANGIOPLASTY; ATHERECTOMY; or stenting.

Biochemistry biochemical

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Abciximab has parent Antibodies, Monoclonal, Humanized

Abciximab has parent Immunoglobulin Fab Fragments

Abciximab member of drug class Anti-thrombotic Agents

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Identifier classification

PrefixChemical substances · AMW:CHEM:

Class12 · Amino Acids, Peptides, and Proteins

Domains

Biochemistry · base Pharmacology · base

Semantic roles

Biochemistry / Concept Pharmacology / Drug

Public labels

Abciximab en · preferred