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Peptide or Protein

DAX-1 Orphan Nuclear Receptor

AMW:CHEM:122491

An orphan nuclear receptor that is implicated in regulation of steroidogenic pathways. It is unlike most orphan nuclear receptors in that it appears to lack an essential DNA-binding domain and instead acts as a transcriptional co-repressor. Mutations in the gene Dax-1 cause congenital adrenal hypoplasia.

Biochemistry biochemical

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