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Peptide or Protein

E2F Transcription Factors

AMW:CHEM:122604

A family of BASIC HELIX-LOOP-HELIX PROTEINS that control expression of a variety of GENES involved in CELL CYCLE regulation. E2F transcription factors typically form heterodimeric complexes with TRANSCRIPTION FACTOR DP1 or transcription factor DP2, and they have N-terminal DNA binding and dimerization domains. E2F transcription factors can act as mediators of transcriptional repression or transcriptional activation.

Biochemistry biochemical

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