Public registry
Nodes
Browse canonical concepts by label, domain, node type, prefix and encoded class.
Current membership scope: Base domain only
| Concept | Node type | Base domain | Matched membership | Identifier |
|---|---|---|---|---|
| Apolipoprotein C-II A 9-kDa protein component of VERY-LOW-DENSITY LIPOPROTEINS. It contains a cofactor for LIPOPROTEIN LIPASE and activates several triacylglycerol lipas… | Lipid | Biochemistry | Base domain | AMW:CHEM:100141 |
| Apolipoprotein C-III A 9-kDa protein component of VERY-LOW-DENSITY LIPOPROTEINS and CHYLOMICRON REMNANTS. Apo C-III, synthesized in the liver, is an inhibitor of LIPOPROT… | Lipid | Biochemistry | Base domain | AMW:CHEM:100142 |
| Apolipoprotein E2 One of three major isoforms of apolipoprotein E. In humans, Apo E2 differs from APOLIPOPROTEIN E3 at one residue 158 where arginine is replaced by cy… | Lipid | Biochemistry | Base domain | AMW:CHEM:100145 |
| Apolipoprotein E3 A 34-kDa glycosylated protein. A major and most common isoform of apolipoprotein E. Therefore, it is also known as apolipoprotein E (ApoE). In human,… | Lipid | Biochemistry | Base domain | AMW:CHEM:100146 |
| Apolipoprotein E4 A major and the second most common isoform of apolipoprotein E. In humans, Apo E4 differs from APOLIPOPROTEIN E3 at only one residue 112 (cysteine is… | Lipid | Biochemistry | Base domain | AMW:CHEM:100147 |
| Apolipoprotein L1 An ApoL protein highly expressed by the liver. It has anti-trypanosomal activity through its ability to permeabilize TRYPANOSOMA membranes. Mutations… | Lipid | Biochemistry | Base domain | AMW:CHEM:100149 |
| Apolipoproteins Protein components on the surface of LIPOPROTEINS. They form a layer surrounding the hydrophobic lipid core. There are several classes of apolipoprot… | Lipid | Biochemistry | Base domain | AMW:CHEM:100130 |
| Apolipoproteins A Structural proteins of the alpha-lipoproteins (HIGH DENSITY LIPOPROTEINS), including APOLIPOPROTEIN A-I and APOLIPOPROTEIN A-II. They can modulate th… | Lipid | Biochemistry | Base domain | AMW:CHEM:100132 |
| Apolipoproteins B Major structural proteins of triacylglycerol-rich LIPOPROTEINS. There are two forms, apolipoprotein B-100 and apolipoprotein B-48, both derived from … | Lipid | Biochemistry | Base domain | AMW:CHEM:100136 |
| Apolipoproteins C A group of apolipoproteins that can readily exchange among the various classes of lipoproteins (HDL; VLDL; CHYLOMICRONS). After lipolysis of TRIGLYCE… | Lipid | Biochemistry | Base domain | AMW:CHEM:100139 |
| Apolipoproteins D A glycoprotein component of HIGH-DENSITY LIPOPROTEINS that transports small hydrophobic ligands including CHOLESTEROL and STEROLS. It occurs in the m… | Lipid | Biochemistry | Base domain | AMW:CHEM:100143 |
| Apolipoproteins E A class of protein components which can be found in several lipoproteins including HIGH-DENSITY LIPOPROTEINS; VERY-LOW-DENSITY LIPOPROTEINS; and CHYL… | Lipid | Biochemistry | Base domain | AMW:CHEM:100144 |
| Apolipoproteins L A family of apolipoproteins occurring in humans that are structurally similar to B-CELL LEUKEMIA 2 FAMILY PROTEINS. In addition to their roles in cho… | Lipid | Biochemistry | Base domain | AMW:CHEM:100148 |
| Apolipoproteins M Apolipoproteins and lipocalins that occur in HIGH-DENSITY LIPOPROTEINS. They bind or transport lipids in the blood including sphingosine-1-phosphate,… | Lipid | Biochemistry | Base domain | AMW:CHEM:100131 |
| Apomorphine A derivative of morphine that is a dopamine D2 agonist. It is a powerful emetic and has been used for that effect in acute poisoning. It has also bee… | Heterocyclic Compound | Biochemistry | Base domain | AMW:CHEM:030048 |
| Apoprotein(a) A large and highly glycosylated protein constituent of LIPOPROTEIN (A). It has very little affinity for lipids but forms disulfide-linkage to APOLIPO… | Lipid | Biochemistry | Base domain | AMW:CHEM:100153 |
| Apoproteins The protein components of a number of complexes, such as enzymes (APOENZYMES), ferritin (APOFERRITINS), or lipoproteins (APOLIPOPROTEINS). | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:120657 |
| Apoptosis Inducing Factor A flavoprotein that functions as a powerful antioxidant in the MITOCHONDRIA and promotes APOPTOSIS when released from the mitochondria. In mammalian … | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:081046 |
| Apoptosis Regulatory Proteins A large group of proteins that control APOPTOSIS. This family of proteins includes many ONCOGENE PROTEINS as well as a wide variety of classes of INT… | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:120427 |
| Apoptosomes Multimeric protein complexes formed in the CYTOSOL that play a role in the activation of APOPTOSIS. They can occur when MITOCHONDRIA become damaged d… | Macromolecule | Biochemistry | Base domain | AMW:CHEM:050005 |
| Apoptotic Protease-Activating Factor 1 A CARD signaling adaptor protein characterized by an N-terminal CARD DOMAIN and C-terminal WD40 REPEATS. It plays a role in the mitochondria-stimulat… | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:120346 |
| Aporphines Dibenzoquinolines derived in plants from (S)-reticuline (BENZYLISOQUINOLINES). | Heterocyclic Compound | Biochemistry | Base domain | AMW:CHEM:030047 |
| Aprepitant A morpholine neurokinin-1 (NK1) receptor antagonist that is used in the management of nausea and vomiting caused by DRUG THERAPY, and for the prevent… | Heterocyclic Compound | Biochemistry | Base domain | AMW:CHEM:030345 |
| Aprindine A class Ib anti-arrhythmia agent used to manage ventricular and supraventricular arrhythmias. | Organic Chemical | Biochemistry | Base domain | AMW:CHEM:021477 |
| Aprotinin A single-chain polypeptide derived from bovine tissues consisting of 58 amino-acid residues. It is an inhibitor of proteolytic enzymes including CHYM… | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:120659 |
| Aptamers, Nucleotide Nucleotide sequences, generated by iterative rounds of SELEX APTAMER TECHNIQUE, that bind to a target molecule specifically and with high affinity. | Nucleic Acid Related | Biochemistry | Base domain | AMW:CHEM:130152 |
| Aptamers, Peptide Peptide sequences, generated by iterative rounds of SELEX APTAMER TECHNIQUE, that bind to a target molecule specifically and with high affinity. | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:120089 |
| Apurinic Acid Hydrolysate of DNA in which purine bases have been removed. | Heterocyclic Compound | Biochemistry | Base domain | AMW:CHEM:030579 |
| Apyrase A calcium-activated enzyme that catalyzes the hydrolysis of ATP to yield AMP and orthophosphate. It can also act on ADP and other nucleoside triphosp… | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:080197 |
| Aquaglyceroporins A subgroup of aquaporins that transport WATER; GLYCEROL; and other small solutes across CELL MEMBRANES. | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:121077 |