Public registry
Nodes
Browse canonical concepts by label, domain, node type, prefix and encoded class.
Current membership scope: Base domain only
| Concept | Node type | Base domain | Matched membership | Identifier |
|---|---|---|---|---|
| Aspartate Kinase An enzyme that catalyzes the formation of beta-aspartyl phosphate from aspartic acid and ATP. Threonine serves as an allosteric regulator of this enz… | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:081772 |
| Aspartate-Ammonia Ligase An enzyme that catalyzes the formation of asparagine from ammonia and aspartic acid, in the presence of ATP. EC 6.3.1.1. | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:080803 |
| Aspartate-Semialdehyde Dehydrogenase An enzyme that catalyzes the conversion of L-aspartate 4-semialdehyde, orthophosphate, and NADP+ to yield L-4-aspartyl phosphate and NADPH. EC 1.2.1.… | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:081086 |
| Aspartate-tRNA Ligase An enzyme that activates aspartic acid with its specific transfer RNA. EC 6.1.1.12. | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:080817 |
| Aspartic Acid One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. I… | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:120008 |
| Aspartic Acid Endopeptidases A sub-subclass of endopeptidases that depend on an ASPARTIC ACID residue for their activity. | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:080555 |
| Aspartic Acid Proteases A subclass of peptide hydrolases that depend on an ASPARTIC ACID residue for their activity. | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:080554 |
| Aspartokinase Homoserine Dehydrogenase A bifunctional protein consisting of aspartokinase, and homoserine dehydrogenase activities. It is found primarily in BACTERIA and in PLANTS. | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:080962 |
| Aspartylglucosylaminase An enzyme that catalyzes the conversion of N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine and water to N-acetyl-beta-D-glucosaminylamine and L-aspa… | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:080265 |
| Aspirin The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibit… | Organic Chemical | Biochemistry | Base domain | AMW:CHEM:021402 |
| Aspirin, Dipyridamole Drug Combination A drug combination of aspirin and dipyridamole that functions as a PLATELET AGGREGATION INHIBITOR, used to prevent THROMBOSIS and STROKE in TRANSIENT… | Organic Chemical | Biochemistry | Base domain | AMW:CHEM:021403 |
| Astatine Astatine. A radioactive halogen with the atomic symbol At, and atomic number 85. Its isotopes range in mass number from 200 to 219 and all have an ex… | Inorganic Chemical | Biochemistry | Base domain | AMW:CHEM:010202 |
| Astemizole Antihistamine drug now withdrawn from the market in many countries because of rare but potentially fatal side effects. | Heterocyclic Compound | Biochemistry | Base domain | AMW:CHEM:030712 |
| Ataxia Telangiectasia Mutated Proteins A group of PROTEIN SERINE-THREONINE KINASES which activate critical signaling cascades in double strand breaks, APOPTOSIS, and GENOTOXIC STRESS such … | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:081554 |
| Ataxin-1 A chromatin-binding factor that represses Notch signaling and associates with RNA. Expansion of the polyglutamine tract by expanded CAG repeats in th… | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:122388 |
| Ataxin-10 An ataxin that is associated with the survival of cerebellar neurons. Expansion of the ATTCT pentanucleotide in the ATXN10 coding region is associate… | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:122390 |
| Ataxin-2 A Poly(A) RNA-binding protein that negatively regulates EGFR ENDOCYTOSIS. An increased risk for developing AMYOTROPHIC LATERAL SCLEROSIS 13 is observ… | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:121297 |
| Ataxin-3 A deubiquitinating enzyme of the ATAXINS family. It functions in protein homeostasis, GENETIC TRANSCRIPTION; CYTOSKELETON regulation, and MYOGENESIS.… | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:080097 |
| Ataxin-7 A component of the STAGA transcription coactivator-HAT complex that functions in Cone Rod Homeobox Protein (CRX)-dependent gene activation. It also s… | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:122389 |
| Ataxins A family of predominantly nuclear proteins that regulate gene transcription and protein degradation. The expansion of CAG trinucleotide repeats in ge… | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:122387 |
| Atazanavir Sulfate An azapeptide and HIV-PROTEASE INHIBITOR that is used in the treatment of HIV INFECTIONS and AIDS in combination with other ANTI-HIV AGENTS. | Heterocyclic Compound | Biochemistry | Base domain | AMW:CHEM:030485 |
| Atenolol A cardioselective beta-1 adrenergic blocker possessing properties and potency similar to PROPRANOLOL, but without a negative inotropic effect. | Organic Chemical | Biochemistry | Base domain | AMW:CHEM:020050 |
| Atomoxetine Hydrochloride A propylamine derivative and selective ADRENERGIC UPTAKE INHIBITOR that is used in the treatment of ATTENTION DEFICIT HYPERACTIVITY DISORDER. | Organic Chemical | Biochemistry | Base domain | AMW:CHEM:020641 |
| Atorvastatin A pyrrole and heptanoic acid derivative, HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITOR (statin), and ANTICHOLESTEREMIC AGENT that is used to reduce s… | Heterocyclic Compound | Biochemistry | Base domain | AMW:CHEM:030269 |
| Atovaquone A hydroxynaphthoquinone that has antimicrobial activity and is being used in antimalarial protocols. | Organic Chemical | Biochemistry | Base domain | AMW:CHEM:021946 |
| ATP Binding Cassette Transporter 1 A superfamily of integral ATP-binding cassette membrane proteins whose expression pattern is consistent with a role in lipid (cholesterol) efflux. It… | Carbohydrate | Biochemistry | Base domain | AMW:CHEM:090094 |
| ATP Binding Cassette Transporter, Subfamily A A large, highly conserved, subfamily of ATP binding cassette transporters structurally characterized by a membrane-spanning domain composed of six AL… | Carbohydrate | Biochemistry | Base domain | AMW:CHEM:090093 |
| ATP Binding Cassette Transporter, Subfamily A, Member 4 An ATP binding cassette sub-family A transporter that translocates 11-cis and all-trans isomers of N-retinylidene-phosphatidylethanolamine (RETINOIDS… | Carbohydrate | Biochemistry | Base domain | AMW:CHEM:090095 |
| ATP Binding Cassette Transporter, Subfamily B A subfamily of transmembrane proteins from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS that are closely related in sequence to ATP BINDING C… | Carbohydrate | Biochemistry | Base domain | AMW:CHEM:090096 |
| ATP Binding Cassette Transporter, Subfamily B, Member 1 A 170-kDa transmembrane glycoprotein from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS. It serves as an ATP-dependent efflux pump for a varie… | Carbohydrate | Biochemistry | Base domain | AMW:CHEM:090097 |