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Browse canonical concepts by label, domain, node type, prefix and encoded class.

10,023 results

Current membership scope: Base domain only

ConceptNode typeBase domainMatched membershipIdentifier
8,11,14-Eicosatrienoic Acid
A 20-carbon-chain fatty acid, unsaturated at positions 8, 11, and 14. It differs from arachidonic acid, 5,8,11,14-eicosatetraenoic acid, only at posi…
LipidBiochemistryBase domainAMW:CHEM:100056
9,10-Dimethyl-1,2-benzanthracene
Polycyclic aromatic hydrocarbon found in tobacco smoke that is a potent carcinogen.
Organic ChemicalBiochemistryBase domainAMW:CHEM:021459
A Kinase Anchor Proteins
A structurally-diverse family of intracellular-signaling adaptor proteins that selectively tether specific protein kinase A subtypes to distinct subc…
Peptide or ProteinBiochemistryBase domainAMW:CHEM:120338
AAA Proteins
A large, highly conserved and functionally diverse superfamily of NTPases and nucleotide-binding proteins that are characterized by a conserved 200 t…
Enzyme or CoenzymeBiochemistryBase domainAMW:CHEM:080141
Abacavir
A carbocyclic nucleoside reverse transcriptase inhibitor with potent and selective anti-HIV activity.
Organic ChemicalBiochemistryBase domainAMW:CHEM:021295
Abatacept
A fusion protein immunoconjugate of the extracellular domain of CTLA4 and the Fc domain of human IgG1. It functions as a T-cell co-stimulation blocke…
Peptide or ProteinBiochemistryBase domainAMW:CHEM:120919
Abciximab
A Fab fragment of the chimeric monoclonal antibody 7E3 that binds to the glycoprotein IIb-IIIa receptor of human platelets, and blocks PLATELET GLYCO…
Peptide or ProteinBiochemistryBase domainAMW:CHEM:120582
Abietanes
A subclass of cyclical DITERPENES that contain the abietane ring structure.
Organic ChemicalBiochemistryBase domainAMW:CHEM:021535
Abiraterone Acetate
An androstene derivative that inhibits STEROID 17-ALPHA-HYDROXYLASE and is used as an ANTINEOPLASTIC AGENT in the treatment of metastatic castration-…
Polycyclic CompoundBiochemistryBase domainAMW:CHEM:040018
ABO Blood-Group System
The major human blood type system which depends on the presence or absence of two antigens A and B. Type O occurs when neither A nor B is present and…
Biological FactorBiochemistryBase domainAMW:CHEM:230036
Abrin
A toxic lectin from the seeds of jequirity, Abrus precatorius L. Very active poison. Five different proteins have so far been isolated: Abrus aggluti…
Enzyme or CoenzymeBiochemistryBase domainAMW:CHEM:080523
Abscisic Acid
Abscission-accelerating plant growth substance isolated from young cotton fruit, leaves of sycamore, birch, and other plants, and from potatoes, lemo…
Organic ChemicalBiochemistryBase domainAMW:CHEM:021024
AC133 Antigen
A member of the prominin family, AC133 Antigen is a 5-transmembrane antigen occurring as several isoforms produced by alternative splicing which are …
CarbohydrateBiochemistryBase domainAMW:CHEM:090086
Acamprosate
Structural analog of taurine that is used for the prevention of relapse in individuals with ALCOHOLISM.
Organic ChemicalBiochemistryBase domainAMW:CHEM:021167
Acarbose
An inhibitor of ALPHA-GLUCOSIDASES that retards the digestion and absorption of DIETARY CARBOHYDRATES in the SMALL INTESTINE.
CarbohydrateBiochemistryBase domainAMW:CHEM:090441
Acebutolol
A cardioselective beta-1 adrenergic antagonist with little effect on the bronchial receptors. The drug has stabilizing and quinidine-like effects on …
Organic ChemicalBiochemistryBase domainAMW:CHEM:020047
Acecainide
A major metabolite of PROCAINAMIDE. Its anti-arrhythmic action may cause cardiac toxicity in kidney failure.
Organic ChemicalBiochemistryBase domainAMW:CHEM:020964
Acedapsone
Acetylated sulfone that is slowly metabolized to give long-term, low blood levels of DAPSONE. It has antimicrobial and antimalarial action, but is ma…
Organic ChemicalBiochemistryBase domainAMW:CHEM:022007
Acenaphthenes
Tricyclic ethylene-bridged naphthalene derivatives. They are found in petroleum residues and coal tar and used as dye intermediates, in the manufactu…
Organic ChemicalBiochemistryBase domainAMW:CHEM:021506
Acenocoumarol
A coumarin that is used as an anticoagulant. Its actions and uses are similar to those of WARFARIN. (From Martindale, The Extra Pharmacopoeia, 30th e…
Heterocyclic CompoundBiochemistryBase domainAMW:CHEM:030444
Acepromazine
A phenothiazine that is used in the treatment of PSYCHOSES.
Organic ChemicalBiochemistryBase domainAMW:CHEM:021979
Acetaldehyde
A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol.…
Organic ChemicalBiochemistryBase domainAMW:CHEM:020180
Acetals
Diethers with the structure -C(OR'')(OR'''), where R'' and R''' are not hydrogen. Mixed acetals have R'' and R''' groups which differ.
Organic ChemicalBiochemistryBase domainAMW:CHEM:021097
Acetamides
Derivatives of acetamide that are used as solvents, as mild irritants, and in organic synthesis.
Organic ChemicalBiochemistryBase domainAMW:CHEM:020199
Acetaminophen
Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blo…
Organic ChemicalBiochemistryBase domainAMW:CHEM:020219
Acetanilides
Compounds based on N-phenylacetamide, that are similar in structure to 2-PHENYLACETAMIDES. They are precursors of many other compounds. They were for…
Organic ChemicalBiochemistryBase domainAMW:CHEM:020218
Acetate Kinase
An enzyme that catalyzes reversibly the phosphorylation of acetate in the presence of a divalent cation and ATP with the formation of acetylphosphate…
Enzyme or CoenzymeBiochemistryBase domainAMW:CHEM:081771
Acetate-CoA Ligase
An enzyme that catalyzes the formation of CoA derivatives from ATP, acetate, and CoA to form AMP, pyrophosphate, and acetyl CoA. It acts also on prop…
Enzyme or CoenzymeBiochemistryBase domainAMW:CHEM:080833
Acetates
Derivatives of ACETIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain the carboxymethane …
Organic ChemicalBiochemistryBase domainAMW:CHEM:020760
Acetazolamide
One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treat…
Organic ChemicalBiochemistryBase domainAMW:CHEM:022062