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A conserved AMINO ACID SEQUENCE located in the intracellular domains of a family of transmembrane proteins involved in various IMMUNE RESPONSES. The …

A conserved AMINO ACID SEQUENCE located in the intracellular domains of a family of transmembrane proteins that negatively regulate the signal transd…

The decline in the function of the IMMUNE SYSTEM during aging.

Meat produced by growing MUSCLE CELLS isolated from animal muscle tissue, in THREE-DIMENSIONAL CELL CULTURE.

Reduction of pharmacologic activity or toxicity of a drug or other foreign substance by a living system, usually by enzymatic action. It includes tho…

The mating of plants or non-human animals which are closely related genetically.

A reduced GENETIC VARIATION and GENETIC FITNESS due to INBREEDING.

Emission of LIGHT by a substance as its temperature is raised. It is sometimes called hot light in contrast to LUMINESCENCE.

An area showing altered staining behavior in the nucleus or cytoplasm of a virus-infected cell. Some inclusion bodies represent virus factories in wh…

A mutation named with the blend of insertion and deletion. It refers to a length difference between two ALLELES where it is unknowable if the differe…

Food processed and manufactured for the nutritional health of children in their first year of life.

Formulations for the nutrition of infants that are substituted for BREAST MILK.

Nutritional physiology of children from birth to 2 years of age.

A biological rhythm with a period longer than 24 hours.

That portion of the electromagnetic spectrum usually sensed as heat. Infrared wavelengths are longer than those of visible light, extending into the …

The act of BREATHING in.

The different ways GENES and their ALLELES interact during the transmission of genetic traits that effect the outcome of GENE EXPRESSION.

The concentration of a compound needed to reduce population growth of organisms, including eukaryotic cells, by 50% in vitro. Though often expressed …

Hyperpolarization of membrane potentials at the SYNAPTIC MEMBRANES of target neurons during NEUROTRANSMISSION. They are local changes which diminish …

Innate immunity systems which recognize presence of pathogens either through detection of damages associated with pathogen effector, e.g., pathogenic…

The development by insects of resistance to insecticides.

The deposit of SEMEN or SPERMATOZOA into the VAGINA to facilitate FERTILIZATION.

The maximum volume of air that can be inspired after reaching the end of a normal, quiet expiration. It is the sum of the TIDAL VOLUME and the INSPIR…

The extra volume of air that can be inspired with maximal effort after reaching the end of a normal, quiet inspiration. Common abbreviation is IRV.

Nucleic acid regulatory sequences that limit or oppose the action of ENHANCER ELEMENTS and define the boundary between differentially regulated gene …

Production and release of insulin from PANCREATIC BETA CELLS that primarily occurs in response to elevated BLOOD GLUCOSE levels.

A signaling pathway that enables cells to adapt to various stressors by modulating protein synthesis. It is initiated by the activation of specific P…

DNA elements that include the component genes and insertion site for a site-specific recombination system that enables them to capture mobile gene ca…

The properties and relationships and biological processes that characterize the nature and function of the SKIN and its appendages.

The internal fragments of precursor proteins (INternal proTEINS) that are autocatalytically removed by PROTEIN SPLICING. The flanking fragments (EXTE…