Public change overview
Recent concepts
Review concepts whose canonical node records were recently created or updated.
Note: this page shows concepts with recent database timestamps. It does not provide a field-by-field edit history because the current schema does not store revision diffs.
| Concept | Change | When | Node type | Domain | Identifier |
|---|---|---|---|---|---|
| Supination Applies to movements of the forearm in turning the palm forward or upward. When referring to the foot, a combination of adduction… |
Updated | Physiological Process | Physiology | AMW:PHYS:110043 | |
| Supine Position The posture of an individual lying face up. |
Updated | State | Physiology | AMW:PHYS:110065 | |
| 3' Flanking Region The region of DNA which borders the 3' end of a transcription unit and where a variety of regulatory sequences are located. |
Updated | Concept | Physiology | AMW:PHYS:050178 | |
| 5' Flanking Region The region of DNA which borders the 5' end of a transcription unit and where a variety of regulatory sequences are located. |
Updated | Concept | Physiology | AMW:PHYS:050179 | |
| Amino Acid Motifs Three-dimensional protein structural elements that are composed of a combination of secondary structures. They include HELIX-LOOP… |
Updated | Concept | Physiology | AMW:PHYS:020182 | |
| Amino Acid Sequence The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of… |
Updated | Concept | Physiology | AMW:PHYS:020081 | |
| Base Composition The relative amounts of the PURINES and PYRIMIDINES in a nucleic acid. |
Updated | Concept | Physiology | AMW:PHYS:020025 | |
| Bay-Region, Polycyclic Aromatic Hydrocarbon A concave exterior region on some POLYCYCLIC AROMATIC HYDROCARBONS that have three phenyl rings in a non-linear arrangement. |
Updated | Concept | Physiology | AMW:PHYS:020155 | |
| Frameshift Mutation A type of mutation in which a number of NUCLEOTIDES deleted from or inserted into a protein coding sequence is not divisible by t… |
Updated | Biochemical Process | Physiology | AMW:PHYS:050353 | |
| Gain of Function Mutation A mutation that results in an increase in a gene's activity or in acquiring a new molecular function or a new pattern of gene exp… |
Updated | Biochemical Process | Physiology | AMW:PHYS:050354 | |
| Germ-Line Mutation Any detectable and heritable alteration in the lineage of germ cells. Mutations in these cells (i.e., generative cells ancestral … |
Updated | Biochemical Process | Physiology | AMW:PHYS:050358 | |
| Immunoglobulin Switch Region A site located in the INTRONS at the 5' end of each constant region segment of a immunoglobulin heavy-chain gene where recombinat… |
Updated | Concept | Physiology | AMW:PHYS:050192 | |
| INDEL Mutation A mutation named with the blend of insertion and deletion. It refers to a length difference between two ALLELES where it is unkno… |
Updated | Biochemical Process | Physiology | AMW:PHYS:050359 | |
| Locus Control Region A regulatory region first identified in the human beta-globin locus but subsequently found in other loci. The region is believed … |
Updated | Concept | Physiology | AMW:PHYS:020114 | |
| Loss of Function Mutation A mutation that causes a decrease in or elimination of a gene product's activity. |
Updated | Biochemical Process | Physiology | AMW:PHYS:050360 | |
| Matrix Attachment Regions Regions of the CHROMATIN or DNA that bind to the NUCLEAR MATRIX. They are found in INTERGENIC DNA, especially flanking the 5' end… |
Updated | Concept | Physiology | AMW:PHYS:020103 | |
| Mutation Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daug… |
Updated | Biochemical Process | Physiology | AMW:PHYS:050329 | |
| Mutation Accumulation Concept which describes the incremental effects of MUTATION in living organisms. |
Updated | Biochemical Process | Physiology | AMW:PHYS:050362 | |
| Mutation, Missense A mutation in which a codon is mutated to one directing the incorporation of a different amino acid. This substitution may result… |
Updated | Biochemical Process | Physiology | AMW:PHYS:050363 | |
| Nucleolus Organizer Region The chromosome region which is active in nucleolus formation and which functions in the synthesis of ribosomal RNA. |
Updated | Concept | Physiology | AMW:PHYS:050097 | |
| Point Mutation A mutation caused by the substitution of one nucleotide for another. This results in the DNA molecule having a change in a single… |
Updated | Biochemical Process | Physiology | AMW:PHYS:050364 | |
| Pseudoautosomal Regions Homologous chromosomal regions at either end of the X CHROMOSOME or Y CHROMOSOME. These two regions pair regularly at male MEIOSI… |
Updated | Concept | Physiology | AMW:PHYS:050154 | |
| Regulatory Sequences, Nucleic Acid Nucleic acid sequences involved in regulating the expression of genes. |
Updated | Concept | Physiology | AMW:PHYS:020105 | |
| Repetitive Sequences, Amino Acid A sequential pattern of amino acids occurring more than once in the same protein sequence. There often is some sequence variation… |
Updated | Concept | Physiology | AMW:PHYS:020094 | |
| Repetitive Sequences, Nucleic Acid Sequences of DNA or RNA that occur in multiple copies. There are several types: INTERSPERSED REPETITIVE SEQUENCES are copies of t… |
Updated | Concept | Physiology | AMW:PHYS:020129 | |
| rRNA Operon Genetic loci which direct transcription of ribosomal RNA in bacterial operons. They are designated rrnB, rrnC, rrnD, etc. accordi… |
Updated | Concept | Physiology | AMW:PHYS:050297 | |
| Segmental Duplications, Genomic Low-copy (2-50) repetitive DNA elements that are highly homologous and range in size from 1000 to 400,000 base pairs. |
Updated | Concept | Physiology | AMW:PHYS:020140 | |
| Sequence Deletion Deletion of sequences of nucleic acids from the genetic material of an individual. |
Updated | Biochemical Process | Physiology | AMW:PHYS:050365 | |
| Sequence Inversion The deletion and reinsertion of a segment of a nucleic acid sequence in the same place, but flipped in an opposite orientation. |
Updated | Biochemical Process | Physiology | AMW:PHYS:050367 | |
| Sex Chromatin In the interphase nucleus, a condensed mass of chromatin representing an inactivated X chromosome. Each X CHROMOSOME, in excess o… |
Updated | Concept | Physiology | AMW:PHYS:050095 |