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Recent concepts

Review concepts whose canonical node records were recently created or updated.

5,556 concepts

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ConceptChangeWhenNode typeDomainIdentifier
Photosensitizing Agents
Drugs that are pharmacologically inactive but when exposed to ultraviolet radiation or sunlight are converted to their active met…
Added Drug Class Pharmacology AMD:CLASS:01268
Physiological Effects of Drugs
Activities which affect organs and systemic functions without regard to a particular disease.
Added Drug Class Pharmacology AMD:CLASS:01078
Phytoestrogens
Compounds derived from plants, primarily ISOFLAVONES that mimic or modulate endogenous estrogens, usually by binding to ESTROGEN …
Added Drug Class Pharmacology AMD:CLASS:01117
Plant Growth Regulators
Any of the hormones produced naturally in plants and active in controlling growth and other functions. There are three primary cl…
Added Drug Class Pharmacology AMD:CLASS:01112
Plasma Substitutes
Any liquid used to replace blood plasma, usually a saline solution, often with serum albumins, dextrans or other preparations. Th…
Added Drug Class Pharmacology AMD:CLASS:01281
Plasticizers
Materials incorporated mechanically in plastics (usually PVC) to increase flexibility, workability or distensibility; due to the …
Added Drug Class Pharmacology AMD:CLASS:01365
Platelet Aggregation Inhibitors
Drugs or agents which antagonize or impair any mechanism leading to blood platelet aggregation, whether during the phases of acti…
Added Drug Class Pharmacology AMD:CLASS:01286
Poisons
Substances which, when ingested, inhaled, or absorbed, or when applied to, injected into, or developed within the body in relativ…
Added Drug Class Pharmacology AMD:CLASS:01366
Poly(ADP-ribose) Polymerase Inhibitors
Chemicals and drugs that inhibit the action of POLY(ADP-RIBOSE)POLYMERASES.
Added Drug Class Pharmacology AMD:CLASS:00923
Potassium Ionophores
Chemical agents that increase the permeability of CELL MEMBRANES to POTASSIUM ions.
Added Drug Class Pharmacology AMD:CLASS:00966
PPAR-gamma Agonists
Hypoglycemic agents that specifically target PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA. They increase tissue sensitivity t…
Added Drug Class Pharmacology AMD:CLASS:01123
Progestins
Compounds that interact with PROGESTERONE RECEPTORS in target tissues to bring about the effects similar to those of PROGESTERONE…
Added Drug Class Pharmacology AMD:CLASS:01119
Prolyl-Hydroxylase Inhibitors
Compounds that inhibit the action of HYDROXYLASES that act on PROLINE to form HYDROXYPROLINE.
Added Drug Class Pharmacology AMD:CLASS:00924
Protease Inhibitors
Compounds which inhibit or antagonize biosynthesis or actions of proteases (ENDOPEPTIDASES).
Added Drug Class Pharmacology AMD:CLASS:00925
Proteasome Inhibitors
Compounds that inhibit the function or proteolytic action of the PROTEASOME.
Added Drug Class Pharmacology AMD:CLASS:00932
Protective Agents
Synthetic or natural substances which are given to prevent a disease or disorder or are used in the process of treating a disease…
Added Drug Class Pharmacology AMD:CLASS:01164
Protein Kinase Inhibitors
Agents that inhibit PROTEIN KINASES.
Added Drug Class Pharmacology AMD:CLASS:00942
Protein Synthesis Inhibitors
Compounds which inhibit the synthesis of proteins. They are usually ANTI-BACTERIAL AGENTS or toxins. Mechanism of the action of i…
Added Drug Class Pharmacology AMD:CLASS:00946
Proteolysis Targeting Chimera
Bifunctional molecules that are designed to recruit E3 UBIQUITIN LIGASE to a specific target protein. Proteolysis targeting chime…
Added Drug Class Pharmacology AMD:CLASS:01347
Proton Ionophores
Chemical agents that increase the permeability of CELL MEMBRANES to PROTONS.
Added Drug Class Pharmacology AMD:CLASS:00953
Provitamins
Precursor forms of vitamins.
Added Drug Class Pharmacology AMD:CLASS:01136
Psychotropic Drugs
A loosely defined grouping of drugs that have effects on psychological function. Here the psychotropic agents include the antidep…
Added Drug Class Pharmacology AMD:CLASS:01261
Pulmonary Surfactants
Substances and drugs that lower the SURFACE TENSION of the mucoid layer lining the PULMONARY ALVEOLI.
Added Drug Class Pharmacology AMD:CLASS:01292
Purinergic Agents
Compounds that act on PURINERGIC RECEPTORS or influence the synthesis, storage, uptake, metabolism, or release of purinergic tran…
Added Drug Class Pharmacology AMD:CLASS:01039
Purinergic Agonists
Compounds that bind to and activate PURINERGIC RECEPTORS.
Added Drug Class Pharmacology AMD:CLASS:01040
Purinergic Antagonists
Drugs that bind to and block the activation of PURINERGIC RECEPTORS.
Added Drug Class Pharmacology AMD:CLASS:01048
Purinergic P1 Receptor Agonists
Compounds that bind to and stimulate PURINERGIC P1 RECEPTORS.
Added Drug Class Pharmacology AMD:CLASS:01041
Purinergic P1 Receptor Antagonists
Compounds that bind to and block the stimulation of PURINERGIC P1 RECEPTORS.
Added Drug Class Pharmacology AMD:CLASS:01049
Purinergic P2 Receptor Agonists
Compounds that bind to and stimulate PURINERGIC P2 RECEPTORS.
Added Drug Class Pharmacology AMD:CLASS:01045
Purinergic P2 Receptor Antagonists
Compounds that bind to and block the stimulation of PURINERGIC P2 RECEPTORS.
Added Drug Class Pharmacology AMD:CLASS:01053