Public change overview
Recent concepts
Review concepts whose canonical node records were recently created or updated.
Note: this page shows concepts with recent database timestamps. It does not provide a field-by-field edit history because the current schema does not store revision diffs.
| Concept | Change | When | Node type | Domain | Identifier |
|---|---|---|---|---|---|
| Regulatory Elements, Transcriptional Nucleotide sequences of a gene that are involved in the regulation of GENETIC TRANSCRIPTION. |
Added | Nucleic Acid Related | Biochemistry | AMW:CHEM:130176 | |
| Replication Origin A unique DNA sequence of a replicon at which DNA REPLICATION is initiated and proceeds bidirectionally or unidirectionally. It co… |
Added | Nucleic Acid Related | Biochemistry | AMW:CHEM:130175 | |
| RNA 5' Terminal Oligopyrimidine Sequence A regulatory sequence found in the 5' terminal regions of a variety of RNA species. The sequence starts with a CYTIDINE, which is… |
Added | Nucleic Acid Related | Biochemistry | AMW:CHEM:130173 | |
| Transcription Initiation Site The first nucleotide of a transcribed DNA sequence where RNA polymerase (DNA-DIRECTED RNA POLYMERASE) begins synthesizing the RNA… |
Added | Nucleic Acid Related | Biochemistry | AMW:CHEM:130177 | |
| Vitamin D Response Element A DNA sequence that is found in the promoter region of vitamin D regulated genes. Vitamin D receptor (RECEPTOR, CALCITRIOL) binds… |
Added | Nucleic Acid Related | Biochemistry | AMW:CHEM:130172 | |
| DNA Copy Number Variations Stretches of genomic DNA that exist in different multiples between individuals. Many copy number variations have been associated … |
Updated | State | Physiology | AMW:PHYS:050374 | |
| DNA Cleavage A reaction that severs one of the covalent sugar-phosphate linkages between NUCLEOTIDES that compose the sugar phosphate backbone… |
Updated | Biochemical Process | Physiology | AMW:PHYS:020053 | |
| DNA Repeat Expansion An increase number of repeats of a genomic, tandemly repeated DNA sequence from one generation to the next. |
Updated | Biochemical Process | Physiology | AMW:PHYS:020142 | |
| Nucleic Acid Conformation The spatial arrangement of the atoms of a nucleic acid or polynucleotide that results in its characteristic 3-dimensional shape. |
Updated | State | Physiology | AMW:PHYS:020164 | |
| Protein Conformation The characteristic 3-dimensional shape of a protein, including the secondary, supersecondary (motifs), tertiary (domains) and qua… |
Updated | State | Physiology | AMW:PHYS:020180 | |
| Acetylation Formation of an acetyl derivative. (Stedman, 25th ed) |
Updated | Biochemical Process | Physiology | AMW:PHYS:020008 | |
| Immunoreceptor Tyrosine-Based Activation Motif A conserved AMINO ACID SEQUENCE located in the intracellular domains of a family of transmembrane proteins involved in various IM… |
Updated | Physiological Process | Physiology | AMW:PHYS:020190 | |
| Immunoreceptor Tyrosine-Based Inhibition Motif A conserved AMINO ACID SEQUENCE located in the intracellular domains of a family of transmembrane proteins that negatively regula… |
Updated | Physiological Process | Physiology | AMW:PHYS:020191 | |
| Anaerobic Threshold The oxygen consumption level above which aerobic energy production is supplemented by anaerobic mechanisms during exercise, resul… |
Added | Parameter | Physiology | AMW:PARAM:125011 | |
| Arterial Pressure The blood pressure in the ARTERIES. It is commonly measured with a SPHYGMOMANOMETER on the upper arm which represents the arteria… |
Added | Parameter | Physiology | AMW:PARAM:105008 | |
| Atrial Pressure The pressure within the CARDIAC ATRIUM. It can be measured directly by using a pressure catheter (see HEART CATHETERIZATION). It … |
Added | Parameter | Physiology | AMW:PARAM:105006 | |
| Blood Cell Count The number of LEUKOCYTES and ERYTHROCYTES per unit volume in a sample of venous BLOOD. A complete blood count (CBC) also includes… |
Added | Parameter | Physiology | AMW:PARAM:115004 | |
| Blood Pressure PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS. |
Added | Parameter | Physiology | AMW:PARAM:105007 | |
| Blood Volume Volume of circulating BLOOD. It is the sum of the PLASMA VOLUME and ERYTHROCYTE VOLUME. |
Added | Parameter | Physiology | AMW:PARAM:105002 | |
| Bone Density The amount of mineral per square centimeter of BONE. This is the definition used in clinical practice. Actual bone density would … |
Added | Parameter | Physiology | AMW:PARAM:160001 | |
| Cardiac Volume The volume of the HEART, usually relating to the volume of BLOOD contained within it at various periods of the cardiac cycle. The… |
Added | Parameter | Physiology | AMW:PARAM:105013 | |
| CD4 Lymphocyte Count The number of CD4-POSITIVE T-LYMPHOCYTES per unit volume of BLOOD. Determination requires the use of a fluorescence-activated flo… |
Added | Parameter | Physiology | AMW:PARAM:115009 | |
| CD4-CD8 Ratio Ratio of T-LYMPHOCYTES that express the CD4 ANTIGEN to those that express the CD8 ANTIGEN. This value is commonly assessed in the… |
Added | Parameter | Physiology | AMW:PARAM:115010 | |
| Cell Count The number of CELLS of a specific kind, usually measured per unit volume or area of sample. |
Added | Parameter | Physiology | AMW:PARAM:115003 | |
| Central Venous Pressure The blood pressure in the central large VEINS of the body. It is distinguished from peripheral venous pressure which occurs in an… |
Added | Parameter | Physiology | AMW:PARAM:105010 | |
| Cerebral Blood Volume Volume of circulating blood in a region of the brain. It is a functional measure of the brain perfusion status which relates chan… |
Added | Parameter | Physiology | AMW:PARAM:105003 | |
| Cerebrospinal Fluid Pressure Manometric pressure of the CEREBROSPINAL FLUID as measured by lumbar, cerebroventricular, or cisternal puncture. Within the crani… |
Added | Parameter | Physiology | AMW:PARAM:160002 | |
| Closing Volume The lung volume at which the dependent lung zones cease to ventilate presumably as a result of airway closure. |
Added | Parameter | Physiology | AMW:PARAM:135010 | |
| Erythrocyte Count The number of RED BLOOD CELLS per unit volume in a sample of venous BLOOD. |
Added | Parameter | Physiology | AMW:PARAM:115005 | |
| Erythrocyte Volume Volume of circulating ERYTHROCYTES . It is usually measured by RADIOISOTOPE DILUTION TECHNIQUE. |
Added | Parameter | Physiology | AMW:PARAM:105004 |