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74,165 results
ConceptNode typeBase domainIdentifier
11-beta-Hydroxysteroid Dehydrogenase Type 1
A low-affinity 11 beta-hydroxysteroid dehydrogenase found in a variety of tissues, most notably in LIVER; LUNG; ADIPOSE TISSUE; vascular tissue; OVAR…
Enzyme or CoenzymeBiochemistryAMW:CHEM:080994
11-beta-Hydroxysteroid Dehydrogenase Type 2
An high-affinity, NAD-dependent 11-beta-hydroxysteroid dehydrogenase that acts unidirectionally to catalyze the dehydrogenation of CORTISOL to CORTIS…
Enzyme or CoenzymeBiochemistryAMW:CHEM:080995
11-beta-Hydroxysteroid Dehydrogenases
Hydroxysteroid dehydrogenases that catalyzes the reversible conversion of CORTISOL to the inactive metabolite CORTISONE. Enzymes in this class can ut…
Enzyme or CoenzymeBiochemistryAMW:CHEM:080993
11-Hydroxycorticosteroids
A group of corticosteroids bearing a hydroxy group at the 11-position.
Hormonal AgentBiochemistryAMW:CHEM:060021
11PMBrand DrugDrug BrandAMD:BRAND:25905
11PMBrand DrugDrug BrandAMD:BRAND:25906
11PMBrand DrugDrug BrandAMD:BRAND:25907
11PMBrand DrugDrug BrandAMD:BRAND:25908
11PMBrand DrugDrug BrandAMD:BRAND:25909
11PMBrand DrugDrug BrandAMD:BRAND:25910
12-Hydroxy-5,8,10,14-eicosatetraenoic Acid
A lipoxygenase metabolite of ARACHIDONIC ACID. It is a highly selective ligand used to label mu-opioid receptors in both membranes and tissue section…
LipidBiochemistryAMW:CHEM:100041
12E7 Antigen
A cell adhesion molecule that, in humans, is encoded by a gene on the PSEUDOAUTOSOMAL REGION of SEX CHROMOSOMES. It functions in CELL ADHESION of T-L…
CarbohydrateBiochemistryAMW:CHEM:090118
14-3-3 Proteins
A large family of signal-transducing adaptor proteins present in wide variety of eukaryotes. They are PHOSPHOSERINE and PHOSPHOTHREONINE binding prot…
Peptide or ProteinBiochemistryAMW:CHEM:120337
14-alpha Demethylase Inhibitors
Compounds that specifically inhibit STEROL 14-DEMETHYLASE. A variety of azole-derived ANTIFUNGAL AGENTS act through this mechanism.
Drug ClassPharmacologyAMD:CLASS:00853
15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid
A stable prostaglandin endoperoxide analog which serves as a thromboxane mimetic. Its actions include mimicking the hydro-osmotic effect of VASOPRESS…
Inorganic ChemicalBiochemistryAMW:CHEM:010145
15-Oxoprostaglandin 13-Reductase
(5Z)-(15S)-11 alpha-Hydroxy-9,15-dioxoprostanoate:NAD(P)+ delta(13)-oxidoreductase. An enzyme active in prostaglandin E and F catabolism. It catalyze…
Enzyme or CoenzymeBiochemistryAMW:CHEM:081124
16,16-Dimethylprostaglandin E2
A synthetic prostaglandin E analog that protects the gastric mucosa, prevents ulceration, and promotes the healing of peptic ulcers. The protective e…
LipidBiochemistryAMW:CHEM:100077
17 alpha-Hydroxyprogesterone Caproate
Hydroxyprogesterone derivative that acts as a PROGESTIN and is used to reduce the risk of recurrent MISCARRIAGE and of PREMATURE BIRTH. It is also us…
Polycyclic CompoundBiochemistryAMW:CHEM:040241
17-alpha-Hydroxypregnenolone
A 21-carbon steroid that is converted from PREGNENOLONE by STEROID 17-ALPHA-HYDROXYLASE. It is an intermediate in the delta-5 pathway of biosynthesis…
Polycyclic CompoundBiochemistryAMW:CHEM:040245
17-alpha-Hydroxyprogesterone
A metabolite of PROGESTERONE with a hydroxyl group at the 17-alpha position. It serves as an intermediate in the biosynthesis of HYDROCORTISONE and G…
Polycyclic CompoundBiochemistryAMW:CHEM:040240
17-Hydroxycorticosteroids
A group of hydroxycorticosteroids bearing a hydroxy group at the 17-position. Urinary excretion of these compounds is used as an index of adrenal fun…
Hormonal AgentBiochemistryAMW:CHEM:060022
17-Hydroxysteroid Dehydrogenases
A class of enzymes that catalyzes the oxidation of 17-hydroxysteroids to 17-ketosteroids. EC 1.1.-.
Enzyme or CoenzymeBiochemistryAMW:CHEM:081000
17-Ketosteroids
Steroids that contain a ketone group at position 17.
Polycyclic CompoundBiochemistryAMW:CHEM:040143
18-Hydroxycorticosterone
11 beta,18,21-Trihydroxypregn-4-ene-3,20-dione.
Polycyclic CompoundBiochemistryAMW:CHEM:040225
18-Hydroxydesoxycorticosterone
An analog of desoxycorticosterone which is substituted by a hydroxyl group at the C-18 position.
Polycyclic CompoundBiochemistryAMW:CHEM:040228
19-Iodocholesterol
19-Iodocholest-5-en-3 beta-ol. A cholesterol derivative usually substituted with radioactive iodine in the 19 position. The compound is an adrenal co…
Polycyclic CompoundBiochemistryAMW:CHEM:040102
1st GenerationDrug ClassPharmacologyAMD:CLASS:00191
1st Line-AntitubercularDrug ClassPharmacologyAMD:CLASS:00192
1st Line-Phenazine DerivativeDrug ClassPharmacologyAMD:CLASS:00193
1st Line-SulfonesDrug ClassPharmacologyAMD:CLASS:00194