NirvanamKnowledge · Cases · Solver

Public change overview

Recent concepts

Review concepts whose canonical node records were recently created or updated.

47,940 concepts

Note: this page shows concepts with recent database timestamps. It does not provide a field-by-field edit history because the current schema does not store revision diffs.

Reset
ConceptChangeWhenNode typeDomainIdentifier
Cannabinoid Receptor Antagonists
Compounds that inhibit or block the activity of CANNABINOID RECEPTORS.
Added Drug Class Pharmacology AMD:CLASS:01007
Cannabinoid Receptor Modulators
Compounds that interact with and modulate the activity of CANNABINOID RECEPTORS.
Added Drug Class Pharmacology AMD:CLASS:01005
Carbamoyl Phosphate Synthetase I Activators
Substances and drugs that stimulate the synthesis or increase the activity of CARBAMOYL PHOSPHATE SYNTHETASE I. Drugs in this cla…
Added Drug Class Pharmacology AMD:CLASS:00892
Carcinogens
Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and non…
Added Drug Class Pharmacology AMD:CLASS:01391
Carcinogens, Environmental
Carcinogenic substances that are found in the environment.
Added Drug Class Pharmacology AMD:CLASS:01392
Cardiotonic Agents
Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATH…
Added Drug Class Pharmacology AMD:CLASS:01247
Cardiotoxins
Agents that have a damaging effect on the HEART. Such damage can occur from ALKYLATING AGENTS; FREE RADICALS; or metabolites from…
Added Drug Class Pharmacology AMD:CLASS:01394
Cardiovascular Agents
Agents that affect the rate or intensity of cardiac contraction, blood vessel diameter, or blood volume.
Added Drug Class Pharmacology AMD:CLASS:01244
Caspase Inhibitors
Endogenous and exogenous compounds and that either inhibit CASPASES or prevent their activation.
Added Drug Class Pharmacology AMD:CLASS:00929
Catechol O-Methyltransferase Inhibitors
Compounds and drugs that inhibit or block the activity of CATECHOL O-METHYLTRANSFERASE enzymes. Drugs in this class are used in m…
Added Drug Class Pharmacology AMD:CLASS:00903
Cathartics
Agents that are used to stimulate evacuation of the bowels.
Added Drug Class Pharmacology AMD:CLASS:01272
Cation Exchange Resins
High molecular weight insoluble polymers which contain functional anionic groups that are capable of undergoing exchange reaction…
Added Drug Class Pharmacology AMD:CLASS:01354
Caustics
Strong alkaline chemicals that destroy soft body tissues resulting in a deep, penetrating type of burn, in contrast to corrosives…
Added Drug Class Pharmacology AMD:CLASS:01313
CCR5 Receptor Antagonists
Compounds and drugs that inhibit or block the activity of CCR5 RECEPTORS.
Added Drug Class Pharmacology AMD:CLASS:00885
Central Nervous System Agents
A class of drugs producing both physiological and psychological effects through a variety of mechanisms. They can be divided into…
Added Drug Class Pharmacology AMD:CLASS:01252
Central Nervous System Depressants
A very loosely defined group of drugs that tend to reduce the activity of the central nervous system. The major groups included h…
Added Drug Class Pharmacology AMD:CLASS:01086
Central Nervous System Stimulants
A loosely defined group of drugs that tend to increase behavioral alertness, agitation, or excitation. They work by a variety of …
Added Drug Class Pharmacology AMD:CLASS:01101
Cerumenolytic Agents
Compounds that disintegrate natural waxy exudates such as EAR WAX.
Added Drug Class Pharmacology AMD:CLASS:00886
Chemical Actions and Uses
A group of pharmacologic activities, effects on living systems and the environment, and modes of employment of drugs and chemical…
Added Drug Class Pharmacology AMD:CLASS:00832
Chemical Warfare Agents
Chemicals that are used to cause the disturbance, disease, or death of humans during WARFARE.
Added Drug Class Pharmacology AMD:CLASS:01367
Chemosterilants
Compounds that cause reproductive sterility in organisms. They are sometimes used to control pest populations by sterilizing male…
Added Drug Class Pharmacology AMD:CLASS:01302
Chloride Channel Agonists
A class of drugs that stimulate chloride ion influx through cell membrane channels.
Added Drug Class Pharmacology AMD:CLASS:00963
Cholagogues and Choleretics
Gastrointestinal agents that stimulate the flow of bile into the duodenum (cholagogues) or stimulate the production of bile by th…
Added Drug Class Pharmacology AMD:CLASS:01273
Cholinergic Agents
Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycl…
Added Drug Class Pharmacology AMD:CLASS:01008
Cholinergic Agonists
Drugs that bind to and activate cholinergic receptors.
Added Drug Class Pharmacology AMD:CLASS:01009
Cholinergic Antagonists
Drugs that bind to but do not activate CHOLINERGIC RECEPTORS, thereby blocking the actions of ACETYLCHOLINE or cholinergic agonis…
Added Drug Class Pharmacology AMD:CLASS:01012
Cholinesterase Inhibitors
Drugs that inhibit cholinesterases. The neurotransmitter ACETYLCHOLINE is rapidly hydrolyzed, and thereby inactivated, by choline…
Added Drug Class Pharmacology AMD:CLASS:00904
Cholinesterase Reactivators
Drugs used to reverse the inactivation of cholinesterase caused by organophosphates or sulfonates. They are an important componen…
Added Drug Class Pharmacology AMD:CLASS:00955
Chromogenic Compounds
Colorless, endogenous or exogenous pigment precursors that may be transformed by biological mechanisms into colored compounds; us…
Added Drug Class Pharmacology AMD:CLASS:01315
Coagulants
Agents that cause clotting.
Added Drug Class Pharmacology AMD:CLASS:01282