Public change overview
Recent concepts
Review concepts whose canonical node records were recently created or updated.
Note: this page shows concepts with recent database timestamps. It does not provide a field-by-field edit history because the current schema does not store revision diffs.
| Concept | Change | When | Node type | Domain | Identifier |
|---|---|---|---|---|---|
| Diuretics, Osmotic Compounds that increase urine volume by increasing the amount of osmotically active solute in the urine. Osmotic diuretics also i… |
Added | Drug Class | Pharmacology | AMD:CLASS:01143 | |
| Diuretics, Potassium Sparing A subclass of diuretics that limits the secretion of POTASSIUM into the URINE. |
Added | Drug Class | Pharmacology | AMD:CLASS:01144 | |
| Dopamine Agents Any drugs that are used for their effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergi… |
Added | Drug Class | Pharmacology | AMD:CLASS:01015 | |
| Dopamine Agonists Drugs that bind to and activate dopamine receptors. |
Added | Drug Class | Pharmacology | AMD:CLASS:01016 | |
| Dopamine D2 Receptor Antagonists Compounds and drugs that bind to and inhibit or block the activation of DOPAMINE D2 RECEPTORS. |
Added | Drug Class | Pharmacology | AMD:CLASS:01017 | |
| Dopamine Uptake Inhibitors Drugs that block the transport of DOPAMINE into axon terminals or into storage vesicles within terminals. Most of the ADRENERGIC … |
Added | Drug Class | Pharmacology | AMD:CLASS:00970 | |
| Emetics Agents that cause vomiting. They may act directly on the gastrointestinal tract, bringing about emesis through local irritant eff… |
Added | Drug Class | Pharmacology | AMD:CLASS:01104 | |
| Emulsifying Agents SURFACE-ACTIVE AGENTS that induce a dispersion of undissolved material throughout a liquid. |
Added | Drug Class | Pharmacology | AMD:CLASS:01377 | |
| Endocrine Disruptors Exogenous agents, synthetic and naturally occurring, which are capable of disrupting the functions of the ENDOCRINE SYSTEM includ… |
Added | Drug Class | Pharmacology | AMD:CLASS:01105 | |
| Endothelin A Receptor Antagonists Compounds and drugs that bind to and inhibit or block the activation of ENDOTHELIN A RECECPTORS. |
Added | Drug Class | Pharmacology | AMD:CLASS:00889 | |
| Endothelin B Receptor Antagonists Compounds and drugs that bind to and inhibit or block the activation of ENDOTHELIN B RECEPTORS. |
Added | Drug Class | Pharmacology | AMD:CLASS:00890 | |
| Endothelin Receptor Antagonists Compounds and drugs that bind to and inhibit or block the activation of ENDOTHELIN RECECPTORS. |
Added | Drug Class | Pharmacology | AMD:CLASS:00888 | |
| Endothelium-Dependent Relaxing Factors Paracrine substances produced by the VASCULAR ENDOTHELIUM with VASCULAR SMOOTH MUSCLE relaxation (VASODILATION) activities. Sever… |
Added | Drug Class | Pharmacology | AMD:CLASS:01251 | |
| Environmental Pollutants Substances or energies, for example heat or light, which when introduced into the air, water, or land threaten life or health of … |
Added | Drug Class | Pharmacology | AMD:CLASS:01382 | |
| Enzyme Activators Compounds or factors that act on a specific enzyme to increase its activity. |
Added | Drug Class | Pharmacology | AMD:CLASS:00891 | |
| Enzyme Inhibitors Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the ca… |
Added | Drug Class | Pharmacology | AMD:CLASS:00896 | |
| Enzyme Reactivators Compounds which restore enzymatic activity by removing an inhibitory group bound to the reactive site of the enzyme. |
Added | Drug Class | Pharmacology | AMD:CLASS:00954 | |
| Epithelial Sodium Channel Agonists Compounds that either stimulate the opening or prevent closure of EPITHELIAL SODIUM ION CHANNELS. |
Added | Drug Class | Pharmacology | AMD:CLASS:00975 | |
| Epithelial Sodium Channel Blockers A subclass of sodium channel blockers that are specific for EPITHELIAL SODIUM CHANNELS. |
Added | Drug Class | Pharmacology | AMD:CLASS:00979 | |
| Estrogens Compounds that interact with ESTROGEN RECEPTORS in target tissues to bring about the effects similar to those of ESTRADIOL. Estro… |
Added | Drug Class | Pharmacology | AMD:CLASS:01115 | |
| Estrogens, Non-Steroidal Non-steroidal compounds with estrogenic activity. |
Added | Drug Class | Pharmacology | AMD:CLASS:01116 | |
| Excitatory Amino Acid Agents Drugs used for their actions on any aspect of excitatory amino acid neurotransmitter systems. Included are drugs that act on exci… |
Added | Drug Class | Pharmacology | AMD:CLASS:01018 | |
| Excitatory Amino Acid Agonists Drugs that bind to and activate excitatory amino acid receptors. |
Added | Drug Class | Pharmacology | AMD:CLASS:01019 | |
| Excitatory Amino Acid Antagonists Drugs that bind to but do not activate excitatory amino acid receptors, thereby blocking the actions of agonists. |
Added | Drug Class | Pharmacology | AMD:CLASS:01020 | |
| Expectorants Agents that increase mucous excretion. Mucolytic agents, that is drugs that liquefy mucous secretions, are also included here. |
Added | Drug Class | Pharmacology | AMD:CLASS:01291 | |
| Explosive Agents Substances that are energetically unstable and can produce a sudden expansion of the material, called an explosion, which is acco… |
Added | Drug Class | Pharmacology | AMD:CLASS:01326 | |
| Factor Xa Inhibitors Endogenous factors and drugs that inhibit or block the activity of FACTOR XA. |
Added | Drug Class | Pharmacology | AMD:CLASS:00936 | |
| Fat Substitutes Compounds used in food or in food preparation to replace dietary fats. They may be carbohydrate-, protein-, or fat-based. Fat sub… |
Added | Drug Class | Pharmacology | AMD:CLASS:01331 | |
| Fatty Acid Synthesis Inhibitors Compounds that interfere with FATTY ACID SYNTHASE resulting in a reduction of FATTY ACIDS. This is a target mechanism in humans o… |
Added | Drug Class | Pharmacology | AMD:CLASS:00877 | |
| Fertility Agents, Female Compounds which increase the capacity to conceive in females. |
Added | Drug Class | Pharmacology | AMD:CLASS:01190 |